Evidence map›Paper›PMID 38243596›Full record

ArticleBiophysical journal2024

Tight coupling of cell width to nucleoid structure in Escherichia coli.

Charles B Howard, Avinoam Rabinovitch, Galit Yehezkel, Arieh Zaritsky

Abstract read
In one paragraph

Article in Biophysical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Charles B HowardDepartment of Life Sciences, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Avinoam RabinovitchDepartment of Physics, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Galit YehezkelDepartment of Life Sciences, Ben-Gurion University of the Negev, Be'er-Sheva, Israel.
Arieh ZaritskyDepartment of Life Sciences, Ben-Gurion University of the Negev, Be'er-Sheva, Israel. Electronic address: ariehzar@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell dimensions of rod-shaped bacteria such as Escherichia coli are connected to mass growth and chromosome replication. During their interdivision cycle (τ min), cells enlarge by elongation only, but at faster growth in richer media, they are also wider. Changes in width W upon nutritional shift-up (shortening τ) occur during the division process. The elusive signal directing the mechanism for W determination is likely related to the tightly linked duplications of the nucleoid (DNA) and the sacculus (peptidoglycan), the only two structures (macromolecules) existing in a single copy that are coupled, temporally and spatially. Six known parameters related to the nucleoid structure and replication are reasonable candidates to convey such a signal, all simple functions of the key number of replication positions n(=C/τ), the ratio between the rates of growth (τ

Indexed as

Escherichia coliEscherichia coli ProteinsBacteriaBacterial ProteinsCell DivisionChromosomes, BacterialDNA ReplicationBacterial ProteinsEscherichia coli Proteins

Identifiers

PMID38243596
PMCPMC10912912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.