ReviewJournal of experimental botany2024
The ascorbate-glutathione cycle coming of age.
Review in Journal of experimental botany, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 168 citations in OpenAlex.
- Trehalose: a potent enhancer of antioxidant responses inPlant signaling & behavior · 2026Article
- Integrated Metabolomic and Bioenergetic Profiling Reveals Axl as a Key Regulator of Macrophage Homeostasis.European journal of immunology · 2026Article
- Shade Nets Modulate Photosynthetic Balance and Antioxidant Homeostasis to Improve Fruit Quality in Ponkan.Plants (Basel, Switzerland) · 2026Article
- Valorisation of the HalophyteFoods (Basel, Switzerland) · 2026Article
- Monodehydroascorbate reductases in plants: integrating ascorbate recycling, redox signaling, and stress adaptation.Redox biology · 2026Review
- Antioxidants Differentially Regulate Non-Photochemical Quenching.Plant, cell & environment · 2026Article
- A WHY1-NADK3-PEX5 module confers drought tolerance by maintaining peroxisomal ROS homeostasis in Brassica napus.The Plant journal : for cell and molecular biology · 2026Article
- Organic Fertilizer Combined with Microbial Inoculant Alleviates Saline-Alkali Stress in Wheat: A Multi-Tissue Analysis.Biology · 2026Article
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- Comparative Analysis ofGenes · 2026Article
- Integrated Physiological and Multi-Omics Analysis Reveals Selenium-Mediated Drought Tolerance inInternational journal of molecular sciences · 2026Article
- Exogenous N-Acetyl-L-cysteine Improves Soybean Saline-Alkali Tolerance by Enhancing the hGSH Pathway to Alleviate Oxidative Damage.Plants (Basel, Switzerland) · 2026Article
- The Dark Side of Antioxidants: When Scavenging ROS Undermines Plant Stress Acclimation.Antioxidants (Basel, Switzerland) · 2026Review
- The Circadian Oscillator Affects Both Glutathione Homeostasis and Its Response to Salt Stress in Arabidopsis thaliana.Plant, cell & environment · 2026Article
- Review
- Reactive oxygen species and oxidative signalling in plants.Essays in biochemistry · 2026Review
- Antioxidant strategies of four native tree species across seasons in urban and peri-urban Atlantic Forest remnants.Environmental monitoring and assessment · 2026Article
- Paclobutrazol and planting density improved onion growth, reduced lodging and enhanced seed yield and quality in mid-hills of Himachal Pradesh.Scientific reports · 2026Article
- Reactive oxygen species in plants: spatiotemporal organization, redox signaling, and stress adaptation.Planta · 2026Review
- Plasmodesmata display dynamic local and systemic redox responses during plant stress.The Plant cell · 2026Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
Concepts regarding the operation of the ascorbate-glutathione cycle and the associated water/water cycle in the processing of metabolically generated hydrogen peroxide and other forms of reactive oxygen species (ROS) are well established in the literature. However, our knowledge of the functions of these cycles and their component enzymes continues to grow and evolve. Recent insights include participation in the intrinsic environmental and developmental signalling pathways that regulate plant growth, development, and defence. In addition to ROS processing, the enzymes of the two cycles not only support the functions of ascorbate and glutathione, they also have 'moonlighting' functions. They are subject to post-translational modifications and have an extensive interactome, particularly with other signalling proteins. In this assessment of current knowledge, we highlight the central position of the ascorbate-glutathione cycle in the network of cellular redox systems that underpin the energy-sensitive communication within the different cellular compartments and integrate plant signalling pathways.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.