ArticlePediatric rheumatology online journal2024
Hypertension as a prominent manifestation secondary to renal artery lesions in pediatric Behcet's disease.
Article in Pediatric rheumatology online journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 6 citations in OpenAlex.
- Bilateral Renal Artery Thrombosis in a Patient With Behçet's Disease Managed With Infliximab Infusions.Cureus · 2026Article
- Behcet's disease presenting as malignant hypertension induced by renovascular hypertension.CEN case reports · 2025Article
- Case Report: A rare case of complex Behçet's disease complicated with acute tubular necrosis and IgA nephropathy, coexists with myelodysplastic syndrome, trisomy 8 and intestinal involvement.Frontiers in immunology · 2025Article
- A narrative review of the role of renal artery intervention in renovascular hypertension.Frontiers in surgery · 2025Review
- Postoperative complications in patients with Behçet's disease.Clinical rheumatology · 2024Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveHypertension caused by vascular Behcet's disease (BD) is an important prognostic factor of paediatric BD. However, much less is known about its clinical features. The objective of this study was to investigate the clinical characteristics of paediatric vascular BD complicated by hypertension.
methodsA retrospective study was carried out in paediatric BD patients complicated by hypertension treated in the Children's Hospital Capital Institute of Paediatrics from Jan 2009 to Dec 2022.
resultsOf 65 BD patients, 6 (9.2%) were complicated by hypertension, 5 patients were female, and the median ages of onset and diagnosis were 9.8 years and 11.3 years, respectively. Three patients were found to have cardiac involvement and hypertensive retinopathy secondary to hypertension. Five of the 6 patients with hypertension had right renal artery involvement, and all of them were treated with glucocorticoids and immunosuppressants. Four patients were treated with biological agents. One patient with severe renal artery stenosis underwent unsuccessful vascular interventional therapy. After 3-6 years of follow-up, five patients were found to have renal atrophy, and one patient was at stable condition.
conclusionHypertension in paediatric BD is mainly caused by renal artery involvement. Early recognition and treatment of vascular involvement in BD is important to prevent poor prognosis.
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