Evidence map›Paper›PMID 38243307›Full record

ArticleAddiction science & clinical practice2024

Buprenorphine misinformation and willingness to treat patients with opioid use disorder among primary care-aligned health care professionals.

Berkeley Franz, Lindsay Y Dhanani, O Trent Hall, Daniel L Brook, Cheyenne Fenstemaker, Janet E Simon, William C Miller

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Addiction science & clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05505227 (Developing a Tailored Stigma Reduction Intervention to Increase Buprenorphine Prescribing Among Rural Primary Care Providers in Ohio), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05505227 naactive not recruitingnot on this map

Developing a Tailored Stigma Reduction Intervention to Increase Buprenorphine Prescribing Among Rural Primary Care Providers in Ohio

TypeinterventionalSponsorOhio UniversityRan2022 to 2025Enrolled400ConditionsOpioid-Related Disorders, Buprenorphine, Social Stigma, Rural Health ServicesArmsStigma-reduction training, Placebo
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
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  8. Observational
  9. Article
  10. Primary Care Clinicians' Attitudes on Digital Care Collaborative Management for Substance Use Disorders.Inquiry : a journal of medical care organization, provision and financing
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Berkeley FranzOhio University Heritage College of Osteopathic Medicine, Department of Social Medicine, Ohio University Athens, Heritage Hall 1, Athens, OH, 45701-2979, USA. franzb@ohio.edu.ORCID 0000-0003-2091-1891
Lindsay Y DhananiRutgers University School of Management and Labor Relations, Piscataway, NJ, USA.
O Trent HallDepartment of Psychiatry and Behavioral Health, Ohio State University Wexner Medical Center, Columbus, OH, USA.
Daniel L BrookOhio State University College of Public Health, Columbus, OH, USA.
Cheyenne FenstemakerOhio University Heritage College of Osteopathic Medicine, Department of Social Medicine, Ohio University Athens, Heritage Hall 1, Athens, OH, 45701-2979, USA.
Janet E SimonOhio University College of Health Sciences and Professions, Athens, OH, USA.
William C MillerGillings School of Public Health , University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.
Ohio University · USRutgers, The State University of New Jersey · USThe Ohio State University · USThe Ohio State University Wexner Medical Center · USUniversity of North Carolina at Chapel Hill · US

Funding

Developing a Tailored Stigma Reduction Intervention to Increase Buprenorphine Prescribing among Rural Primary Care Providers in OhioR34DA057160 · NIDA · OHIO UNIVERSITY ATHENS · PI FRANZ, BERKELEY · 2022 to 2024
$698k
NIDA NIH HHS R34 DA057160NIDA NIH HHS R34DA057160
6 · The paper itself

Abstract

backgroundBuprenorphine is a highly effective medication for opioid use disorder that is underused by health care professionals (HCPs). Medications for opioid use disorder (MOUD) misinformation may be an important barrier to buprenorphine access, but most implementation strategies have aimed to reduce negative attitudes towards patients with opioid use disorder (OUD) rather than misinformation specific to buprenorphine use. In this study, we assessed the degree to which HCPs endorsed misinformation related to buprenorphine, and whether this is associated with willingness to provide care to patients with OUD.

methodsIn September-December of 2022, we surveyed HCPs practicing in Ohio (n = 409). Our primary outcomes included a previously validated 5-item measure of HCP willingness to treat patients with OUD, and three other measures of willingness. Our key independent variable was a study-developed 5-item measure of endorsement of misinformation related to buprenorphine, which assessed beliefs in buprenorphine's efficacy in managing withdrawal symptoms and reducing overdose deaths as well as beliefs about the role of buprenorphine in achieving remission. We computed descriptive and bivariable statistics and fit regression models predicting each outcome of interest.

resultsOn average, HCPs scored 2.34 out of 5.00 (SD = 0.80) on the composite measure of buprenorphine misinformation. 48.41% of participants endorsed at least one piece of misinformation. The most endorsed items were that buprenorphine is ineffective at reducing overdose deaths (M = 2.75, SD =0 .98), and that its use substitutes one drug for another (M = 2.41, SD = 1.25). HCP endorsement of buprenorphine misinformation significantly and negatively predicted willingness to work with patients with OUD (b = - 0.34; 95% CI - 0.46, - 0.21); intentions to increase time spent with this patient population (b = - 0.36; 95% CI - 5.86, - 1.28); receipt of an X-waiver (OR = 0.54, 95% CI 0.38, 0.77); and intention to get an X-waiver (OR: 0.56; 95% CI: 0.33-0.94).

conclusionsMisinformation is common among HCPs and associated with lower willingness to treat patients with OUD. Implementation strategies to increase MOUD use among HCPs should specifically counter misinformation related to buprenorphine. CLINICAL

trial registrationClinicaltrials.gov, NCT05505227. Registered 17 August 2022, https://clinicaltrials.gov/ct2/show/NCT05505227.

Indexed as

BuprenorphineDrug OverdoseOpioid-Related DisordersAnalgesics, OpioidCommunicationHealth PersonnelHumansOpiate Substitution TreatmentPrimary Health CareAnalgesics, OpioidBuprenorphineAddiction medicineBuprenorphineMisinformationOpioid-related disordersPrimary care

Identifiers

PMID38243307
PMCPMC10797921
OpenAlexW4391026973

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.