ArticleTrials2024
Robotic versus Electromagnetic bronchoscopy for pulmonary LesIon AssessmeNT: the RELIANT pragmatic randomized trial.
Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05705544 (Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT), which is not on this map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Robotic Versus Electromagnetic Bronchoscopy for Pulmonary LesIon AssessmeNT: (the RELIANT Trial)
Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- Shape-sensing robotic-assisted bronchoscopy (ss-RAB) for peripheral pulmonary nodules: learning curve and diagnostic performance from an initial multicenter experience in China.Respiratory research · 2026Trial
- Robotic versus Electromagnetic Bronchoscopy for Peripheral Pulmonary Lesions: A Randomized Trial (RELIANT).American journal of respiratory and critical care medicine · 2025Trial
- Intraoperative Nodule Localization in Non-Small-Cell Lung Cancer: Existing and Emerging Techniques.Cancers · 2026Review
- Digital tomosynthesis for navigational bronchoscopy: a clinical practice review.Journal of thoracic disease · 2025Review
- Contemporary Concise Review 2024: New Techniques in Interventional Pulmonology.Respirology (Carlton, Vic.) · 2025Review
- Radial-Probe Endobronchial Ultrasound as Part of Different Navigational Bronchoscopy Modalities in Combination with Cryobiopsy Could Be More than a Confirmation Tool: A Case Series.Diagnostics (Basel, Switzerland) · 2025Article
- Development and deployment of robots in a bronchoscopy suite.Breathe (Sheffield, England) · 2025Review
- Review
- Ion robotic bronchoscopy laser ablation and Da Vinci robotic segmentectomy for bilateral pulmonary nodules: a case report.Translational lung cancer research · 2025Article
- Article
- Robotic-assisted bronchoscopy-advancing lung cancer management.Frontiers in surgery · 2025Review
- Preoperative localization of pulmonary nodules by electromagnetic navigation bronchoscopy combined with methylene blue injection.Journal of thoracic disease · 2024Article
- State of the art: peripheral diagnostic bronchoscopy.Journal of thoracic disease · 2024Review
- Early comparison robotic bronchoscopy versus electromagnetic navigational bronchoscopy for biopsy of pulmonary nodules in a thoracic surgery practice.Journal of robotic surgery · 2024Article
Corrections and comments
- Update of
Authors and funding
16 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundRobotic-assisted bronchoscopy has recently emerged as an alternative to electromagnetic navigational bronchoscopy for the evaluation of peripheral pulmonary lesions. While robotic-assisted bronchoscopy is proposed to have several advantages, such as an easier learning curve, it is unclear if it has comparable diagnostic utility as electromagnetic navigational bronchoscopy.
methodsRobotic versus Electromagnetic bronchoscopy for pulmonary LesIon AssessmeNT (RELIANT) is an investigator-initiated, single-center, open label, noninferiority, cluster randomized controlled trial conducted in two operating rooms at Vanderbilt University Medical Center. Each operating room (OR) is assigned to either robotic-assisted or electromagnetic navigational bronchoscopy each morning, with each OR day considered one cluster. All patients undergoing diagnostic bronchoscopy for evaluation of a peripheral pulmonary lesion in one of the two operating rooms are eligible. Schedulers, patients, and proceduralists are blinded to daily group allocations until randomization is revealed for each operating room each morning. The primary endpoint is the diagnostic yield defined as the proportion of cases yielding lesional tissue. Secondary and safety endpoints include procedure duration and procedural complications. Enrolment began on March 6, 2023, and will continue until 202 clusters have been accrued, with expected enrolment of approximately 400 patients by the time of completion in March of 2024. DISCUSSION: RELIANT is a pragmatic randomized controlled trial that will compare the diagnostic yield of the two most commonly used bronchoscopic approaches for sampling peripheral pulmonary lesions. This will be the first known cluster randomized pragmatic trial in the interventional pulmonology field and the first randomized controlled trial of robotic-assisted bronchoscopy.
trial registrationClinicalTrials.gov registration (NCT05705544) on January 30, 2023.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.