Evidence map›Paper›PMID 38243067›Full record

ArticleScientific reports2024

The application of synthetic antibacterial minerals to combat topical infections: exploring a mouse model of MRSA infection.

Keith D Morrison, Meghan B Reiss, Tanya D Tanner, Travis R Gollott, Gabriela G Loots, Nicole M Collette

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Keith D MorrisonNuclear and Chemical Sciences Division, Physical and Life Sciences, Lawrence Livermore National Laboratory, Livermore, CA, USA. morrison30@llnl.gov.
Meghan B ReissBiosciences and Biotechnology Division, Physical and Life Sciences, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Tanya D TannerBiosciences and Biotechnology Division, Physical and Life Sciences, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Travis R GollottBiosciences and Biotechnology Division, Physical and Life Sciences, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Gabriela G LootsBiosciences and Biotechnology Division, Physical and Life Sciences, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Nicole M ColletteBiosciences and Biotechnology Division, Physical and Life Sciences, Lawrence Livermore National Laboratory, Livermore, CA, USA.
Lawrence Livermore National Laboratory · US

Funding

Lawrence Livermore National Laboratory 9-LW-029
6 · The paper itself

Abstract

The development of new antibiotics has stalled, and novel strategies are needed as we enter the age of antibiotic resistance. Certain naturally occurring clays have been shown to be effective in killing antibiotic resistant bacteria. However, these natural clays are too variable to be used in clinical settings. Our study shows that synthetic antibacterial minerals exhibit potent antibacterial activity against topical MRSA infections and increase the rate of wound closure relative to controls. The antibacterial minerals maintain a redox cycle between Fe

Indexed as

Methicillin-Resistant Staphylococcus aureusAnimalsAnti-Bacterial AgentsClayMiceMineralsReactive Oxygen SpeciesAnti-Bacterial AgentsClayMineralsReactive Oxygen Species

Identifiers

PMID38243067
PMCPMC10798972
OpenAlexW4391017403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.