Evidence map›Paper›PMID 38242691›Full record

ArticleeNeuro2024

High-Gamma Activity Is Coupled to Low-Gamma Oscillations in Precentral Cortices and Modulates with Movement and Speech.

Jeffrey Z Nie, Robert D Flint, Prashanth Prakash, Jason K Hsieh, Emily M Mugler, Matthew C Tate, Joshua M Rosenow, Marc W Slutzky

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Jeffrey Z NieSouthern Illinois University School of Medicine, Springfield 62794, Illinois.ORCID https://orcid.org/0000-0001-5213-4252
Robert D FlintDepartments of Neurology, Northwestern University, Chicago 60611, Illinois.ORCID https://orcid.org/0000-0002-0281-5778
Prashanth PrakashDepartments of Neurology, Northwestern University, Chicago 60611, Illinois.
Jason K HsiehDepartments of Neurology, Northwestern University, Chicago 60611, Illinois.
Emily M MuglerDepartments of Neurology, Northwestern University, Chicago 60611, Illinois.
Matthew C TateDepartments of Neurology, Northwestern University, Chicago 60611, Illinois.
Joshua M RosenowDepartments of Neurology, Northwestern University, Chicago 60611, Illinois.
Marc W SlutzkyDepartments of Neurology, Northwestern University, Chicago 60611, Illinois mslutzky@northwestern.edu.ORCID https://orcid.org/0000-0003-2269-7729
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
MULTIDISCIPLINARY CLINICAL AND TRANSLATIONAL SCIENCE (MCTS) PROGRAM (UL1)UL1RR025741 · NCRR · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GREENLAND, PHILIP · 2008 to 2011
$24.7M
Multidisciplinary Clinical and Translational Science (MCTS) Program (UL1)UL1TR000150 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LLOYD-JONES, DONALD M · 2012 to 2013
$10.1M
Combining myoelectric training with sleep-based memory reactivation to improve motor recovery after strokeR01NS112942 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PALLER, KEN A, SLUTZKY, MARC W. · 2019 to 2023
$2.8M
Designing brain machine interfaces to drive plasticity and enhance recovery after brain injuryR01NS094748 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DO, AN, SLUTZKY, MARC W. · 2015 to 2019
$2.3M
A wearable myoelectric computer interface to reduce muscle co-activation in acute and chronic strokeR01NS099210 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SLUTZKY, MARC W. · 2016 to 2020
$1.7M
Action Potentials vs. Field Potentials as Inputs to a Brain-Machine InterfaceK08NS060223 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SLUTZKY, MARC W. · 2007 to 2011
$839k
The Cortical Dynamics of Motor Activity During Speech ProductionF32DC015708 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI MUGLER, EMILY M · 2016 to 2016
$53k
NCATS NIH HHS UL1 TR000150NCATS NIH HHS UL1 TR001422NCRR NIH HHS UL1 RR025741NIDCD NIH HHS F32 DC015708NINDS NIH HHS K08 NS060223NINDS NIH HHS R01 NS094748NINDS NIH HHS R01 NS099210NINDS NIH HHS R01 NS112942
6 · The paper itself

Abstract

Planning and executing motor behaviors requires coordinated neural activity among multiple cortical and subcortical regions of the brain. Phase-amplitude coupling between the high-gamma band amplitude and the phase of low frequency oscillations (theta, alpha, beta) has been proposed to reflect neural communication, as has synchronization of low-gamma oscillations. However, coupling between low-gamma and high-gamma bands has not been investigated. Here, we measured phase-amplitude coupling between low- and high-gamma in monkeys performing a reaching task and in humans either performing finger-flexion or word-reading tasks. We found significant coupling between low-gamma phase and high-gamma amplitude in multiple sensorimotor and premotor cortices of both species during all tasks. This coupling modulated with the onset of movement. These findings suggest that interactions between the low and high gamma bands are markers of network dynamics related to movement and speech generation.

Indexed as

Motor CortexSpeechBrainHumansMovementECoGgammaLFPsmovementphase–amplitude couplingspeech

Identifiers

PMID38242691
PMCPMC10867721
OpenAlexW4391019889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.