Evidence map›Paper›PMID 38242551›Full record

ArticleRMD open2024

Pregnancy outcomes in women with rheumatoid arthritis: an 11-year French nationwide study.

Laura Pina Vegas, Jérôme Drouin, Alain Weill, Rosemary Dray-Spira

Open access · goldAbstract read
In one paragraph

Article in RMD open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
8.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Family Planning and Rheumatoid Arthritis.Current rheumatology reports · 2025
    Review
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laura Pina VegasÉpidémiologie des produits de santé, ANSM-CNAM, EPI-PHARE, Saint-Denis, France laura.pinavegas@aphp.fr.ORCID 0000-0002-2735-1148
Jérôme DrouinÉpidémiologie des produits de santé, ANSM-CNAM, EPI-PHARE, Saint-Denis, France.
Alain WeillÉpidémiologie des produits de santé, ANSM-CNAM, EPI-PHARE, Saint-Denis, France.
Rosemary Dray-SpiraÉpidémiologie des produits de santé, ANSM-CNAM, EPI-PHARE, Saint-Denis, France.
Conservatoire National des Arts et Métiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRheumatoid arthritis (RA) can affect women of childbearing age. The management of patients with RA during pregnancy has evolved over the past decades, especially with the availability of new therapeutic molecules.

objectivesTo describe pregnancy in women with RA, to compare pregnancy outcomes with those of women in the general population and to compare pregnancy outcomes in women with active and inactive RA.

methodsUsing the French National Health Data System, we identified all pregnancies ending between 2010 and 2020 in patients with and without RA. Characteristics were described. Active RA was defined by conventional synthetic/biological/targeted synthetic disease-modifying antirheumatic drug initiation, systemic or intra-articular corticosteroid administration and/or RA-related hospitalisation. Pregnancy outcomes were compared computing multivariable logistic marginal regression model using generalised estimating equation (GEE).

resultsWe included 11 792 RA and 10 413 681 non-RA pregnancies. Among RA pregnancies, 74.5% ended in live births and 0.4% in stillbirths. RA pregnancies resulted more frequently in preterm births (adjusted OR (OR

conclusionPregnancies in women with RA were associated with more adverse outcomes, especially if the disease was active. These findings should encourage physicians to closely monitor RA during this crucial period.

Indexed as

Arthritis, RheumatoidPregnancy ComplicationsPremature BirthCesarean SectionFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeAntirheumatic AgentsArthritis, RheumatoidEpidemiology

Identifiers

PMID38242551
PMCPMC10806509
OpenAlexW4391037938

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.