Evidence map›Paper›PMID 38241000›Full record

ArticleInternational journal of behavioral medicine2025

Infectious Illness Symptoms Are Associated with Elevated Anxiety in a Sample of Sexual and Gender Minority Young Adults During the COVID-19 Pandemic.

Chitra S Iyer, Joshua M Schrock, Anthony Johnson, Pamina M Gorbach, Sue Siminski, Michael E Newcomb, Thomas W McDade, Brian Mustanski

Open access · greenAbstract read
In one paragraph

Article in International journal of behavioral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Chitra S IyerInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, 625 N Michigan Ave, Suite 14, Chicago, IL, 60611, USA.
Joshua M SchrockInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, 625 N Michigan Ave, Suite 14, Chicago, IL, 60611, USA.ORCID http://orcid.org/0000-0001-9564-0737
Anthony JohnsonInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, 625 N Michigan Ave, Suite 14, Chicago, IL, 60611, USA.
Pamina M GorbachDepartment of Epidemiology, University of California, Los Angeles, 650 Charles E Young Dr S, Room 41-295, Los Angeles, CA, 90095, USA.
Sue SiminskiFrontier Science, 4033 Maple Road, Amherst, NY, 14226, USA.
Michael E NewcombInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, 625 N Michigan Ave, Suite 14, Chicago, IL, 60611, USA.
Thomas W McDadeDepartment of Anthropology, Northwestern University, 1810 Hinman Avenue, Evanston, IL, 60208, USA.
Brian MustanskiInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, 625 N Michigan Ave, Suite 14, Chicago, IL, 60611, USA. brian@northwestern.edu.
Northwestern University · USFrontier Science & Technology Research Foundation · USUniversity of California, Los Angeles · US

Funding

The RADAR cohort study of multilevel Influences on HIV and substance useU01DA036939 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian Mustanski, Michael E Newcomb · 2014 to 2026
$29.5M
Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO) Second Bridge Funding SupplementU24DA044554 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GORBACH, PAMINA MAE, SIMINSKI, SUZANNE M. · 2017 to 2022
$6.8M
NIDA NIH HHS 3U01DA036939-06S1NIDA NIH HHS 3U24DA044554- 04S1NIDA NIH HHS U01 DA036939NIDA NIH HHS U24 DA044554
6 · The paper itself

Abstract

backgroundTo evaluate whether infectious illness symptoms (IIS) are associated with generalized anxiety symptoms during the COVID-19 pandemic in sexual/gender (SGM) minority young adults assigned male at birth (AMAB).

methodFour hundred eighteen participants (median age = 25; range, 20-40) were recruited through RADAR, an ongoing Chicago-based cohort study of SGM-AMAB between September 2020 and February 2021. Participants completed online surveys. A subset (n = 145) provided dried blood spot samples to assess SARS-CoV-2 serostatus.

resultsOne hundred twenty participants (28.7%) had GAD-7 scores of 10 or greater, which indicates generalized anxiety symptoms that may be clinically significant. In a binomial logistic regression model adjusting age, gender identity, race/ethnicity, substance use, and HIV status, the authors found that having a higher IIS count since March 1, 2020, was associated with greater odds of having a GAD-7 score of 10 or greater (OR = 1.14; 95% CI, 1.04, 1.25; P = 0.007). This effect was more pronounced in a binomial logistic regression model adjusting for the same covariates but using current IIS count as the independent variable (OR = 1.39; 95% CI, 1.13, 1.74; P = 0.002).

conclusionAmong SGM-AMAB young adults, those who experienced ISS reported higher scores on the GAD-7, a widely used and validated screening measure for generalized anxiety symptoms. These findings highlight the importance of screening for anxiety disorders when patients present with IIS in clinical settings and psychobehavioral health follow-ups when indicated.

Indexed as

AnxietyCOVID-19Sexual and Gender MinoritiesAdultChicagoFemaleHumansMaleSARS-CoV-2Young AdultAnxietyCOVID-19Infectious illness symptomsLGBTQ+Mental healthYouth

Identifiers

PMID38241000
PMCPMC11258203
OpenAlexW4391023422

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.