Evidence map›Paper›PMID 38240956›Full record

ArticleAnnals of biomedical engineering2024

Functional Assessment of Human Articular Cartilage Using Second Harmonic Generation (SHG) Imaging: A Feasibility Study.

Ziad Abusara, Eng Kuan Moo, Ifaz Haider, Claire Timmermann, Sue Miller, Scott Timmermann, Walter Herzog

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of biomedical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ziad AbusaraHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada. zabusara@ucalgary.ca.
Eng Kuan MooHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada.ORCID http://orcid.org/0000-0001-6363-6063
Ifaz HaiderHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada.
Claire TimmermannHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada.
Sue MillerMcCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Scott TimmermannMcCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Walter HerzogHuman Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada.
University of Calgary · CA

Funding

the Carleton University internal start-up research fund 186725the Natural Sciences and Engineering Research Council of Canada (NSERC) Discovery gran DGECR-2023-00346
6 · The paper itself

Abstract

Many arthroscopic tools developed for knee joint assessment are contact-based, which is challenging for in vivo application in narrow joint spaces. Second harmonic generation (SHG) laser imaging is a non-invasive and non-contact method, thus presenting an attractive alternative. However, the association between SHG-based measures and cartilage quality has not been established systematically. Here, we investigated the feasibility of using image-based measures derived from SHG microscopy for objective evaluation of cartilage quality as assessed by mechanical testing. Human tibial plateaus harvested from nine patients were used. Cartilage mechanical properties were determined using indentation stiffness (E

Indexed as

Cartilage, ArticularSecond Harmonic Generation MicroscopyCollagenExtracellular MatrixFeasibility StudiesHumansCollagenBone-cartilage allograftsCollagen networkIndentation stiffnessKnee jointMultiphoton laser microscopyOsteoarthritisStreaming potential

Identifiers

PMID38240956
OpenAlexW4391023318

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.