Evidence map›Paper›PMID 38240877›Full record

ArticleParasitology research2024

Genetic polymorphism and clustering of the Plasmodium cynomolgi Duffy binding protein 1 region II of recent macaque isolates from Peninsular Malaysia.

Eira Nurfarisha Mohd Latif, Naqib Rafieqin Noordin, Shahhaziq Shahari, Amirah Amir, Yee-Ling Lau, Fei-Wen Cheong, Mohd Lutfi Abdullah, Mun Yik Fong

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Article in Parasitology research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed, 1 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Eira Nurfarisha Mohd LatifDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Naqib Rafieqin NoordinDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Shahhaziq ShahariDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Amirah AmirDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Yee-Ling LauDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Fei-Wen CheongDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia.
Mohd Lutfi AbdullahNational Wildlife Forensic Laboratory, Ex-Situ Conservation Division Department of Wildlife and National Parks Peninsular Malaysia, Kuala Lumpur, Malaysia.
Mun Yik FongDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia. fongmy@um.edu.my.
University of Malaya · MY

Funding

Ministry of Higher Education, Malaysia FRGS/1/2020/SKK0/UM/01/3
6 · The paper itself

Abstract

Plasmodium cynomolgi is a simian malaria parasite that has been increasingly infecting humans. It is naturally present in the long-tailed and pig-tailed macaques in Southeast Asia. The P. cynomolgi Duffy binding protein 1 region II [PcDBP1(II)] plays an essential role in the invasion of the parasite into host erythrocytes. This study investigated the genetic polymorphism, natural selection and haplotype clustering of PcDBP1(II) from wild macaque isolates in Peninsular Malaysia. The genomic DNA of 50 P. cynomolgi isolates was extracted from the macaque blood samples. Their PcDBP1(II) gene was amplified using a semi-nested PCR, cloned into a plasmid vector and subsequently sequenced. The polymorphism, natural selection and haplotypes of PcDBP1(II) were analysed using MEGA X and DnaSP ver.6.12.03 programmes. The analyses revealed high genetic polymorphism of PcDBP1(II) (π = 0.026 ± 0.004; H

Indexed as

Plasmodium cynomolgiPlasmodium knowlesiAnimalsCluster AnalysisGenetic VariationHumansMacaca fascicularisMalaysiaPhylogenyPolymorphism, GeneticProtozoan ProteinsProtozoan ProteinsDuffy binding protein 1Genetic polymorphismHaplotypesNatural selectionPeninsular MalaysiaPlasmodium cynomolgi

Identifiers

PMID38240877
OpenAlexW4391036194

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.