Evidence map›Paper›PMID 38240745›Full record

ArticleeLife2024

Analysis of NIH K99/R00 awards and the career progression of awardees.

Nicole C Woitowich, Sarah R Hengel, Christopher Solis, Tauras P Vilgalys, Joel Babdor, Daniel J Tyrrell

Abstract read
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Degree Background and NIH K-to-R01 Transition Among Investigators Using Experimental Neuroscience to Advance Psychiatry.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026
    Article
  3. Article
  4. Article
  5. Guide to assembling a successful K99/R00 application.Journal of clinical and translational science · 2023
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nicole C Woitowich *Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, United States.ORCID https://orcid.org/0000-0002-3449-2547
Sarah R Hengel *Department of Biology, Tufts University, Medford, United States.ORCID https://orcid.org/0000-0002-0408-8623
Christopher SolisDepartment of Health, Nutrition, and Food Sciences, Florida State University, Tallahassee, United States.
Tauras P VilgalysSection of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, United States.
Joel BabdorDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania, Philadelphia, United States.
Daniel J TyrrellDivision of Molecular and Cellular Pathology, Department of Pathology, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, United States.ORCID https://orcid.org/0000-0002-0811-6724

Funding

Shu complex and RAD52 function in DNA damage recognition and subsequent repairR00ES033738 · NIEHS · TUFTS UNIVERSITY MEDFORD · PI HENGEL, SARAH R · 2023 to 2025
$747k
Post-translational mechanisms of cardiac adaptation during unloadingR00HL151825 · NHLBI · FLORIDA STATE UNIVERSITY · PI SOLIS OCAMPO, CHRISTOPHER · 2023 to 2025
$747k
Cerebrovascular Mitochondrial Function in Aging and Ischemic InjuryR00AG068309 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI TYRRELL, DANIEL · 2022 to 2024
$744k
Post-translational mechanisms of cardiac adaptation during unloadingK99HL151825 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SOLIS OCAMPO, CHRISTOPHER · 2020 to 2021
$210k
Characterizing variation and adaptation in the immune response to plague (Y. pestis) through single-cell sequencing and ancient genomicsF32GM140568 · NIGMS · UNIVERSITY OF CHICAGO · PI VILGALYS, TAURAS P · 2021 to 2023
$205k
NHLBI NIH HHS K99 HL151825NHLBI NIH HHS R00 HL151825NIA NIH HHS R00 AG068309NIEHS NIH HHS R00 ES033738NIGMS NIH HHS F32 GM140568NIH HHS HL151825NIH HHS R00AG068309NIH HHS R00ES033738
6 · The paper itself

Abstract

Many postdoctoral fellows and scholars who hope to secure tenure-track faculty positions in the United States apply to the National Institutes of Health (NIH) for a Pathway to Independence Award. This award has two phases (K99 and R00) and provides funding for up to 5 years. Using NIH data for the period 2006-2022, we report that ~230 K99 awards were made every year, representing up to ~$250 million annual investment. About 40% of K99 awardees were women and ~89% of K99 awardees went on to receive an R00 award annually. Institutions with the most NIH funding produced the most recipients of K99 awards and recruited the most recipients of R00 awards. The time between a researcher starting an R00 award and receiving a major NIH award (such as an R01) ranged between 4.6 and 7.4 years, and was significantly longer for women, for those who remained at their home institution, and for those hired by an institution that was not one of the 25 institutions with the most NIH funding. Shockingly, there has yet to be a K99 awardee at a historically Black college or university. We go on to show how K99 awardees flow to faculty positions, and to identify various factors that influence the future success of individual researchers and, therefore, also influence the composition of biomedical faculty at universities in the United States.

Indexed as

Awards and PrizesBiomedical ResearchFemaleHealth PersonnelHumansMaleNational Institutes of Health (U.S.)Research PersonnelUnited Statescomputational biologyfundinggrantshumanmeta-sciencenetworkssystems biology

Identifiers

PMID38240745
PMCPMC10945599

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.