ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2024
Highly Customizable 3D Microelectrode Arrays for In Vitro and In Vivo Neuronal Tissue Recordings.
Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed.
- Hydrogen releasing biomaterials for bone regeneration: mechanisms, design strategies, and applications.Bioactive materials · 2027Review
- Bioinspired organic materials for seamless neurohybrid interfaces: from material design to living electronics.Materials horizons · 2026Review
- Three-dimensional microelectrode arrays forBiomedical engineering letters · 2026Review
- Flexible Multimodal Neural Probe with Integrated Three-Electrode Aptameric Sensing for In Vivo Monitoring of Dopamine Dynamics and Neural Activity.ACS chemical neuroscience · 2026Article
- From trade-offs to translation: An interdisciplinary roadmap for neurotechnology.Science advances · 2026Review
- Anatomical effects of ablation of the anterior retina in small animal eyes.BMC ophthalmology · 2026Article
- Focusing optical phased array for tissue interrogation with improved side-lobe suppression and simplified beam steering.Biomedical optics express · 2026Article
- Microelectrode arrays cultured with in vitro neural networks for motion control tasks: encoding and decoding progress and advances.Microsystems & nanoengineering · 2025Review
- UV Laser-Induced Carbon Microelectrode Arrays for Neuronal Recordings.Advanced healthcare materials · 2025Article
- Neural vs Neuromorphic Interfaces: Where Are We Standing?Chemical reviews · 2025Review
- Harnessing Intelligence from Brain Cells In Vitro.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2025Review
- Inkjet-Printed 3D Sensor Arrays with FIB-Induced Electrode Refinement for Low-Noise Amperometric Recordings in hiPSC-Derived Brain Organoids.ACS sensors · 2025Article
- Advanced Brain-on-a-Chip for Wetware Computing: A Review.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Electrical Stimulation of Cells: Drivers, Technology, and Effects.Chemical reviews · 2025Review
- Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Intraretinal Electrophysiology and Resistivity Profiles of WT and RCS Rat Retina.Sensors (Basel, Switzerland) · 2025Article
- Flexible 3D Kirigami Probes for In Vitro and In Vivo Neural Applications.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- A local de-insulation method and its application in neural microneedle array.Microsystems & nanoengineering · 2025Article
- Micropillars in Cell Mechanobiology: Design, Fabrication, Characterization, and Biosensing Applications.Small science · 2025Review
- In vivo microelectrode arrays for neuroscience.Nature reviews. Methods primers · 2025Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Planar microelectrode arrays (MEAs) for - in vitro or in vivo - neuronal signal recordings lack the spatial resolution and sufficient signal-to-noise ratio (SNR) required for a detailed understanding of neural network function and synaptic plasticity. To overcome these limitations, a highly customizable three-dimensional (3D) printing process is used in combination with thin film technology and a self-aligned template-assisted electrochemical deposition process to fabricate 3D-printed-based MEAs on stiff or flexible substrates. Devices with design flexibility and physical robustness are shown for recording neural activity in different in vitro and in vivo applications, achieving high-aspect ratio 3D microelectrodes of up to 33:1. Here, MEAs successfully record neural activity in 3D neuronal cultures, retinal explants, and the cortex of living mice, thereby demonstrating the versatility of the 3D MEA while maintaining high-quality neural recordings. Customizable 3D MEAs provide unique opportunities to study neural activity under regular or various pathological conditions, both in vitro and in vivo, and contribute to the development of drug screening and neuromodulation systems that can accurately monitor the activity of large neural networks over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.