ArticleJournal of the American Heart Association2024
Timing of Initiation of Extracorporeal Membrane Oxygenation Support and Outcomes Among Patients With Cardiogenic Shock.
Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Extracorporeal membrane oxygenation initiation timing and prognosis: a systematic review and meta-analysis.BMC cardiovascular disorders · 2026Pooled it
- Associated factors for in-hospital mortality in patients with fulminant myocarditis: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2026Pooled it
- SCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Guideline
- ECMO for patients with obesity: evidence and practice.Intensive care medicine · 2026Review
- Timing of veno-arterial extracorporeal membrane oxygenation in cardiogenic shock: A systematic review and meta-analysis.Journal of intensive medicine · 2026Article
- Preoperative extracorporeal membrane oxygenation is associated with improved outcomes in emergent surgical pulmonary embolectomy.General thoracic and cardiovascular surgery · 2026Article
- ECMO Before Heart Transplantation: Early Implantation and Optimized Assistance with the Eurosets ECMOLIFE System and Landing Advance-A Case Report.Reports (MDPI) · 2026Article
- Extracorporeal membrane oxygenation for systemic lupus erythematosus: An ELSO registry analysis.Perfusion · 2026Article
- Timing of intervention in cardiogenic shock management: A systematic review and network meta-analysis.Journal of education and health promotion · 2026Review
- Venoarterial extracorporeal membrane oxygenation in adults with cardiogenic shock.Frontiers in cardiovascular medicine · 2026Review
- ECMO in hinterland-feasibility and challenges (case-based narrative review).Frontiers in medicine · 2026Review
- Pathogenesis of MRSA-influenza co-infection: implications for ECMO therapeutic strategies - a mini-review.Frontiers in immunology · 2026Review
- A Proposed Algorithm for the Management of Patients with Cardiogenic Shock Based on Contemporary Knowledge and Gaps in Evidence.Journal of cardiovascular development and disease · 2025Review
- Extracorporeal Membrane Oxygenation for Acute Respiratory Failure in a Dog.Animals : an open access journal from MDPI · 2025Article
- Ideal Timing of Coronary Artery Bypass Grafting After Non-ST-Segment Elevation Myocardial Infarction.The Annals of thoracic surgery · 2025Article
- Successful Management of Severe Refractory ARDS in Hemophagocytic Lymphohistiocytosis with VV-ECMO: A Case Report and Analysis.The American journal of case reports · 2025Article
- Prognostic implication of venoarterial extracorporeal membrane oxygenation in acute myocardial infarction-related cardiogenic shock.Journal of intensive care · 2025Article
- Rapid Cycle Deliberate Practice Extracorporeal Membrane Oxygenation Simulation in the Cardiac Catheterization Laboratory.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- SCAI/EAPCI/ACVC Expert Consensus Statement on Cardiogenic Shock in Women: This statement was endorsed by the Heart Failure Society of America (HFSA).Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- National Outcomes of Venoarterial Extracorporeal Life Support in Patients with Chronic Kidney Disease.Surgery open science · 2025Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundVenoarterial extracorporeal membrane oxygenation (ECMO) provides full hemodynamic support for patients with cardiogenic shock, but optimal timing of ECMO initiation remains uncertain. We sought to determine whether earlier initiation of ECMO is associated with improved survival in cardiogenic shock. METHODS AND
resultsWe analyzed adult patients with cardiogenic shock who received venoarterial ECMO from the international Extracorporeal Life Support Organization (ELSO) registry from 2009 to 2019, excluding those cannulated following an operation. Multivariable logistic regression evaluated the association between time from admission to ECMO initiation and in-hospital death. Among 8619 patients (median, 56.7 [range, 44.8-65.6] years; 33.5% women), the median duration from admission to ECMO initiation was 14 (5-32) hours. Patients who had ECMO initiated within 24 hours (n=5882 [68.2%]) differed from those who had ECMO initiated after 24 hours, with younger age, more preceding cardiac arrest, and worse acidosis. After multivariable adjustment, patients with ECMO initiated >24 hours after admission had higher risk of in-hospital death (adjusted odds ratio, 1.20 [95% CI, 1.06-1.36];
conclusionsLonger delays from admission to ECMO initiation were associated with higher a mortality rate in a large-scale, international registry. Our analysis supports optimization of door-to-support time and the avoidance of inappropriately delayed ECMO initiation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.