Evidence map›Paper›PMID 38240210›Full record

Observational studyJournal of the American Heart Association2024

Atrial Fibrillation Detection and Ischemic Stroke Recurrence in Cryptogenic Stroke: A Retrospective, Multicenter, Observational Study.

Kenichi Todo, Shuhei Okazaki, Ryosuke Doijiri, Hidekazu Yamazaki, Kazutaka Sonoda, Junpei Koge, Tomonori Iwata, Yuji Ueno, Hiroshi Yamagami, Naoto Kimura and 10 more

Open access · goldAbstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Atrial fibrillation in Retinal Artery Occlusions.Cardiology and cardiovascular medicine · 2025
    Article
  10. A Year in Review: Atrial Fibrillation 2024.The Journal of innovations in cardiac rhythm management · 2025
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 8 institutions in 1 country.

Kenichi TodoDepartment of Neurology Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0001-7711-3466
Shuhei OkazakiDepartment of Neurology Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0002-5789-2893
Ryosuke DoijiriDepartment of Neurology Iwate Prefectural Central Hospital Iwate Japan.ORCID 0000-0002-2830-9232
Hidekazu YamazakiDepartment of Neurology Yokohama Shintoshi Neurosurgical Hospital Yokohama Kanagawa Japan.ORCID 0000-0002-1835-2886
Kazutaka SonodaDepartment of Neurology Saiseikai Fukuoka General Hospital Fukuoka Japan.
Junpei KogeDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Osaka Japan.ORCID 0000-0002-9632-2164
Tomonori IwataDepartment of Neurology Tokai University Hiratsuka Kanagawa Japan.
Yuji UenoDepartment of Neurology Juntendo University Faculty of Medicine Tokyo Japan.ORCID 0000-0002-8617-3695
Hiroshi YamagamiDepartment of Stroke Neurology National Hospital Organization Osaka National Hospital Osaka Japan.ORCID 0000-0001-8133-3314
Naoto KimuraDepartment of Neurosurgery Iwate Prefectural Central Hospital Iwate Japan.
Masafumi MorimotoDepartment of Neurosurgery Yokohama Shintoshi Neurosurgical Hospital Yokohama Kanagawa Japan.
Daisuke KondoDepartment of Neurology Saiseikai Fukuoka General Hospital Fukuoka Japan.
Masatoshi KogaDepartment of Cerebrovascular Medicine National Cerebral and Cardiovascular Center Osaka Japan.ORCID 0000-0002-6758-4026
Eiichiro NagataDepartment of Neurology Tokai University Hiratsuka Kanagawa Japan.ORCID 0000-0001-6902-8309
Nobukazu MiyamotoDepartment of Neurology Juntendo University Faculty of Medicine Tokyo Japan.ORCID 0000-0003-3037-169X
Yoko KimuraDepartment of Stroke Neurology National Hospital Organization Osaka National Hospital Osaka Japan.ORCID 0000-0002-0984-9030
Yasufumi GonDepartment of Neurology Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0002-3907-1741
Tsutomu SasakiDepartment of Neurology Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0001-8726-978X
Hideki MochizukiDepartment of Neurology Osaka University Graduate School of Medicine Osaka Japan.ORCID 0000-0002-0874-7542
CRYPTON‐ICM Registry Investigators
The University of Osaka · JPIwate Prefectural Central Hospital · JPJuntendo University · JPNational Cerebral and Cardiovascular Center · JPOhkawara Neurosurgical Hospital · JPOsaka National Hospital · JPSaiseikai Fukuoka General Hospital · JPTokai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) is known to be a strong risk factor for stroke. However, the risk of stroke recurrence in patients with cryptogenic stroke with AF detected after stroke by an insertable cardiac monitor (ICM) is not well known. We sought to evaluate the risk of ischemic stroke recurrence in patients with cryptogenic stroke with and without ICM-detected AF. METHODS AND

resultsWe retrospectively reviewed patients with cryptogenic stroke who underwent ICM implantation at 8 stroke centers in Japan. Cox regression models were developed using landmark analysis and time-dependent analysis. We set the target sample size at 300 patients based on our estimate of the annualized incidence of ischemic stroke recurrence to be 3% in patients without AF detection and 9% in patients with AF detection. Of the 370 patients, 121 were found to have AF, and 110 received anticoagulation therapy after AF detection. The incidence of ischemic stroke recurrence was 4.0% in 249 patients without AF detection and 5.8% in 121 patients with AF detection (

conclusionsThe risk of ischemic stroke recurrence in patients with cryptogenic stroke with ICM-detected AF, 90% of whom were subsequently anticoagulated, was not higher than in those without ICM-detected AF.

Indexed as

Atrial FibrillationIschemic StrokeStrokeElectrocardiography, AmbulatoryHumansRetrospective Studiesatrial fibrillationcryptogenic strokeischemic stroke

Identifiers

PMID38240210
PMCPMC11056161
OpenAlexW4391034900

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.