Evidence map›Paper›PMID 38240159›Full record

ArticleCirculation. Cardiovascular quality and outcomes2024

Classification Algorithm to Distinguish Between Type 1 and Type 2 Myocardial Infarction in Administrative Claims Data.

Jason H Wasfy, Mary Price, Sharon-Lise T Normand, James L Januzzi, Cian P McCarthy, John Hsu

Open access · greenAbstract read
In one paragraph

Article in Circulation. Cardiovascular quality and outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jason H WasfyCardiology Division (J.H.W., J.L.J., C.P.M.), Massachusetts General Hospital, Harvard Medical School, Boston.ORCID 0000-0002-0871-5970
Mary PriceDepartment of Medicine (M.P., J.H.), Massachusetts General Hospital, Harvard Medical School, Boston.
Sharon-Lise T NormandDepartment of Health Care Policy, Harvard Medical School, and the Department of Biostatistics, Harvard Chan School of Public Health, Boston, MA (S.-L.T.N.).ORCID 0000-0001-7027-4769
James L JanuzziCardiology Division (J.H.W., J.L.J., C.P.M.), Massachusetts General Hospital, Harvard Medical School, Boston.ORCID 0000-0002-8338-1798
Cian P McCarthyCardiology Division (J.H.W., J.L.J., C.P.M.), Massachusetts General Hospital, Harvard Medical School, Boston.
John HsuDepartment of Medicine (M.P., J.H.), Massachusetts General Hospital, Harvard Medical School, Boston.ORCID 0000-0001-8244-231X
Harvard University · USMassachusetts General Hospital · US

Funding

Impact of the COVID-19 Pandemic on Patients with Alzheimer's Disease and Alzheimer's Disease Related DementiasU01AG076478 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI HSU, JOHN · 2021 to 2025
$4.1M
Improving the Health Status of Individuals with Type 2 Myocardial InfarctionK23HL167659 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Cian Patrick McCarthy · 2023 to 2026
$786k
NHLBI NIH HHS K23 HL167659NIA NIH HHS U01 AG076478
6 · The paper itself

Abstract

backgroundType 2 myocardial infarction (T2MI) and type 1 myocardial infarction (T1MI) differ with respect to demographics, comorbidities, treatments, and clinical outcomes. Reliable quality and outcomes assessment depends on the ability to distinguish between T1MI and T2MI in administrative claims data. As such, we aimed to develop a classification algorithm to distinguish between T1MI and T2MI that could be applied to claims data.

methodsUsing data for beneficiaries in a Medicare accountable care organization contract in a large health care system in New England, we examined the distribution of MI diagnosis codes between 2018 to 2021 and the patterns of care and coding for beneficiaries with a hospital discharge diagnosis

resultsAfter application of inclusion and exclusion criteria, 7759 hospitalizations for myocardial infarction remained (46.5% T1MI and 53.5% T2MI; mean age, 79±10.3 years; 47% female). In the classification algorithm, female gender (odds ratio, 1.26 [95% CI, 1.11-1.44]), Black race relative to White race (odds ratio, 2.48 [95% CI, 1.76-3.48]), and diagnoses of COVID-19 (odds ratio, 1.74 [95% CI, 1.11-2.71]) or hypertensive emergency (odds ratio, 1.46 [95% CI, 1.00-2.14]) were associated with higher odds of the hospitalization being for T2MI versus T1MI. When applied to the testing sample, the C-statistic of the full model was 0.83. Comparison of classified T2MI and observed T2MI suggest the possibility of substantial misclassification both before and after the T2MI code.

conclusionsA simple classification algorithm appears to be able to differentiate between hospitalizations for T1MI and T2MI before and after the T2MI code was introduced. This could facilitate more accurate longitudinal assessments of acute myocardial infarction quality and outcomes.

Indexed as

MedicareMyocardial InfarctionAgedAged, 80 and overAlgorithmsComorbidityFemaleHumansMaleNew EnglandUnited StatesclassificationepidemiologyhospitalizationMedicaremyocardial infarction

Identifiers

PMID38240159
PMCPMC11087697
OpenAlexW4391028831

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.