Evidence map›Paper›PMID 38240130›Full record

ArticleJournal of veterinary internal medicine

Spontaneous remission and relapse of diabetes mellitus in a male dog.

Mariola B Rak, Chen Gilor, Stijn J M Niessen, Eva Furrow

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 3 countries.

Mariola B RakDepartment of Small Animal Clinical Sciences at the College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA.
Chen GilorDepartment of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA.ORCID https://orcid.org/0000-0003-0393-4135
Stijn J M NiessenDepartment of Clinical Science and Services, Royal Veterinary College, University of London, Hertfordshire, UK.ORCID https://orcid.org/0009-0000-9667-6678
Eva FurrowDepartment of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota, USA.ORCID https://orcid.org/0000-0002-7339-2354
University of Florida · USUniversity of London · GBUniversity of Minnesota · USUniversity of Tennessee at Knoxville · US

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR002494 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, WEISDORF, DANIEL J · 2018 to 2022
$34.9M
The role of zinc transporters and dietary zinc in calcium oxalate urolithiasisK01OD019912 · OD · UNIVERSITY OF MINNESOTA · PI FURROW, EVA · 2015 to 2021
$760k
NCATS NIH HHS UL1 TR002494NIH HHS K01 OD019912NIH HHS K01-OD019912NIH HHS UL1TR002494
6 · The paper itself

Abstract

An 8-year-old male neutered Miniature Schnauzer was diagnosed with diabetes mellitus based on fasting hyperglycemia and glucosuria after a 2-week history of polydipsia and periuria, in line with the Agreeing Language in Veterinary Endocrinology consensus definition. Treatment of insulin and dietary management was initiated. The insulin dose was gradually reduced and eventually discontinued over the next year based on spot blood glucose concentrations that revealed euglycemia or hypoglycemia. After discontinuation, the dog remained free of clinical signs for 1 year until it was again presented for polyuria/polydipsia with fasting hyperglycemia and glucosuria. Insulin therapy was resumed and continued for the remainder of the dog's life. Although diabetic remission often occurs in cats and humans, the presumed etiopathogenesis of pancreatic beta cell loss makes remission rare in dogs, except for cases occurring with diestrus or pregnancy. This case demonstrates that diabetic remission is possible in dogs, even in cases without an identifiable reversible trigger.

Indexed as

Cat DiseasesDiabetes MellitusDog DiseasesHyperglycemiaAnimalsBlood GlucoseCatsDogsFemaleHumansInsulinMalePolydipsiaPregnancyRecurrenceRemission, SpontaneousBlood GlucoseInsulinbeta cellsglucotoxicityinsulinobesitypancreatitisschnauzer

Identifiers

PMID38240130
PMCPMC10937483
OpenAlexW4391029476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.