ArticleFrontiers in psychiatry2023
ChatGPT is not ready yet for use in providing mental health assessment and interventions.
Article in Frontiers in psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 5 of them syntheses that pooled it.
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Who cites it
58 citing papers in PubMed, 5 syntheses or guidelines pooled it, 98 citations in OpenAlex.
- The Application and Ethical Implication of Generative AI in Mental Health: Systematic Review.JMIR mental health · 2025Pooled it
- Unveiling the Potential of Large Language Models in Transforming Chronic Disease Management: Mixed Methods Systematic Review.Journal of medical Internet research · 2025Pooled it
- Use of generative artificial intelligence (AI) in psychiatry and mental health care: a systematic review.Acta neuropsychiatrica · 2024Pooled it
- The application of ChatGPT in nursing: a bibliometric and visualized analysis.Frontiers in medicine · 2024Pooled it
- Applications of large language models in psychiatry: a systematic review.Frontiers in psychiatry · 2024Pooled it
- How do Artificial Intelligence chatbots respond to questions from adolescent personas about their eating, body weight or appearance?Child and adolescent mental health · 2026Article
- Benchmarking Generative Artificial Intelligence Against Human Judgment in Eating Disorder Case Recognition and Treatment Recommendations.The International journal of eating disorders · 2026Article
- Generative Large Language Models in Mental Health Care Settings: Systematic Review and Meta-Analysis.JMIR AI · 2026Review
- Artificial Intelligence-Assisted Generation of Case Scenarios and Multiple-Choice Questions in Psychiatry: A Pilot Study.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2026Article
- Explaining GPTs' schema of depression: A machine behavior analysis.Journal of psychopathology and clinical science · 2026Article
- A Secure User Interface for Preclinical Evaluation of AI in Patient Portal Message Management: Tutorial.JMIR medical informatics · 2026Article
- Review
- Science Is About Thinking: How Can We Protect Thinking Time in a Distracted Digital World?Brain sciences · 2026Review
- Application of Artificial Intelligence for Predicting Sports Injuries and Customizing Personalized Prevention Strategies: A Scoping Review.Bioengineering (Basel, Switzerland) · 2026Review
- Clinical Plausibility in Large Language Model Robustness Testing for Medicine: A Scoping Review.Journal of medical systems · 2026Article
- Evaluating the clinical safety of large language models in oral cancer-related patient communication: a repeated-prompt observational study.BMC oral health · 2026Observational
- Exploring the potential of ChatGPT as a digital advisor in acute psychiatric crises: a feasibility study.Der Nervenarzt · 2026Article
- A systematic review of the limitations of large language models in generating healthcare content.PLOS digital health · 2026Article
- Alignment of Large Language Model Responses With Human Therapists in Motivational Interviewing.JAMA network open · 2026Article
- More details, less variability? A crossover design study on the impact of information granularity on ChatGPT's training program stability.Biology of sport · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 12 institutions in 10 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Psychiatry is a specialized field of medicine that focuses on the diagnosis, treatment, and prevention of mental health disorders. With advancements in technology and the rise of artificial intelligence (AI), there has been a growing interest in exploring the potential of AI language models systems, such as Chat Generative Pre-training Transformer (ChatGPT), to assist in the field of psychiatry. Objective: Our study aimed to evaluates the effectiveness, reliability and safeness of ChatGPT in assisting patients with mental health problems, and to assess its potential as a collaborative tool for mental health professionals through a simulated interaction with three distinct imaginary patients. Methods: Three imaginary patient scenarios (cases A, B, and C) were created, representing different mental health problems. All three patients present with, and seek to eliminate, the same chief complaint (i.e., difficulty falling asleep and waking up frequently during the night in the last 2°weeks). ChatGPT was engaged as a virtual psychiatric assistant to provide responses and treatment recommendations. Results: In case A, the recommendations were relatively appropriate (albeit non-specific), and could potentially be beneficial for both users and clinicians. However, as complexity of clinical cases increased (cases B and C), the information and recommendations generated by ChatGPT became inappropriate, even dangerous; and the limitations of the program became more glaring. The main strengths of ChatGPT lie in its ability to provide quick responses to user queries and to simulate empathy. One notable limitation is ChatGPT inability to interact with users to collect further information relevant to the diagnosis and management of a patient's clinical condition. Another serious limitation is ChatGPT inability to use critical thinking and clinical judgment to drive patient's management. Conclusion: As for July 2023, ChatGPT failed to give the simple medical advice given certain clinical scenarios. This supports that the quality of ChatGPT-generated content is still far from being a guide for users and professionals to provide accurate mental health information. It remains, therefore, premature to conclude on the usefulness and safety of ChatGPT in mental health practice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.