Evidence map›Paper›PMID 38239625›Full record

ArticleFrontiers in genome editing2023

Computational analysis of cas proteins unlocks new potential in HIV-1 targeted gene therapy.

Will Dampier, Rachel Berman, Michael R Nonnemacher, Brian Wigdahl

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genome editing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. CRISPR/Cas9 for achieving postintervention HIV control.Current opinion in HIV and AIDS · 2025
    Review
  3. Review
  4. Delivering CRISPR to the HIV-1 reservoirs.Frontiers in microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Will DampierDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Rachel BermanDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Michael R NonnemacherDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Brian WigdahlDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, PA, United States.
Drexel University · USInstitute for Molecular Medicine · USThomas Jefferson University · US

Funding

Viral Gene Editing and Bioinformatics Core for Institution # 269291P30MH092177 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI Ilker Kudret Sariyer · 2011 to 2026
$24.9M
Gene editing strategies to target HIV for elimination in periphery and brainR01MH110360 · NIMH · DREXEL UNIVERSITY · PI Ilker Kudret Sariyer, Brian Wigdahl · 2016 to 2026
$7.3M
Interdisciplinary And Translational Research Training In NeurohivT32MH079785 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI Kamel Khalili · 2008 to 2026
$5.4M
NIMH NIH HHS P30 MH092177NIMH NIH HHS R01 MH110360NIMH NIH HHS T32 MH079785
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CRiSPR/Cascure strategygene therapyguideRNAHIV-1

Identifiers

PMID38239625
PMCPMC10794619
OpenAlexW4390585048

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.