Evidence map›Paper›PMID 38239533›Full record

ArticleCureus2023

The Intertwined Relationship Between an Overactive Thyroid and an Overactive Mind: A Case Report and Review of Literature.

Sushma Bilichodu Rangappa, Aditi Sharma, Sreekant Avula, Deepak Chandramohan, Vinod Sharma

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Sushma Bilichodu RangappaPsychiatry, Chamarajanagar Institute of Medical Sciences, Mysore, IND.
Aditi SharmaPsychiatry, The Wright Center for Graduate Medical Education, Scranton, USA.
Sreekant AvulaDiabetes, Endocrinology, and Metabolism, University of Minnesota, Minneapolis, USA.
Deepak ChandramohanInternal Medicine and Nephrology, University of Alabama at Birmingham, Birmingham, USA.
Vinod SharmaPsychiatry, The Wright Center for Graduate Medical Education, Scranton, USA.
University of Alabama at Birmingham · USMysore Medical College · INPediatric Nephrology of Alabama · USThe Wright Center for Graduate Medical Education · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report presents the clinical scenario of a 45-year-old male patient who exhibited acute psychiatric symptoms as the initial manifestation of Graves' disease, a common etiology of hyperthyroidism. The patient presented with severe agitation, persecutory delusions, and auditory hallucinations, raising concerns about his mental health. Detailed diagnostic evaluations revealed thyroid dysfunction characterized by markedly low thyroid-stimulating hormone (TSH) levels, elevated free T4 levels, and increased total T3 levels, indicative of thyrotoxicosis. Elevated thyroid-stimulating immunoglobulin (TSI) levels further confirmed the diagnosis of Graves' disease. The patient received treatment with methimazole and propranolol to manage the hyperthyroidism, leading to the resolution of psychiatric symptoms. This case emphasizes the importance of considering thyroid function in patients presenting with acute psychiatric disturbances. This literature review explores the intricate relationship between hyperthyroidism, a condition characterized by the excessive production of thyroid hormones, and its impact on psychological and cognitive processes. Understanding the connection between an overactive thyroid and an overactive mind is crucial for clinicians and researchers to provide comprehensive care and treatment for affected individuals.

Indexed as

graveshormoneshyperthyroidmaniapsychosisthyroidthyrotoxicosis

Identifiers

PMID38239533
PMCPMC10794160
OpenAlexW4389941793

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.