Evidence map›Paper›PMID 38238958›Full record

ArticleZhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology2023

[Research progress on AMPK activation in nonalcoholic fatty liver disease].

X Y Ye, T X Li, Z W Huang, W W Fu, Q Li

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

X Y YeDepartment of General Surgery (Hepatopancreatobiliary Surgery), the First Affiliated Hospital of Southwest Medical University & Academician (Expert) Workstation of Sichuan Province, the First Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
T X LiDepartment of General Surgery (Hepatopancreatobiliary Surgery), the First Affiliated Hospital of Southwest Medical University & Academician (Expert) Workstation of Sichuan Province, the First Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Z W HuangDepartment of General Surgery (Hepatopancreatobiliary Surgery), the First Affiliated Hospital of Southwest Medical University & Academician (Expert) Workstation of Sichuan Province, the First Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
W W FuDepartment of General Surgery (Hepatopancreatobiliary Surgery), the First Affiliated Hospital of Southwest Medical University & Academician (Expert) Workstation of Sichuan Province, the First Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.
Q LiDepartment of General Surgery (Hepatopancreatobiliary Surgery), the First Affiliated Hospital of Southwest Medical University & Academician (Expert) Workstation of Sichuan Province, the First Affiliated Hospital of Southwest Medical University, Luzhou 646000, China.

Funding

Luzhou Municipal People's Government-Southwest Medical University Science and Technology Strategic Cooperation Project 2021LZXNYD-Z01National Natural Science Foundation of China 82170587
6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) occurrence and progression are associated with lipid accumulation, insulin resistance, inflammation, liver damage, fibrosis, and other factors. AMP-dependent protein kinase (AMPK) is a key molecule that regulates bioenergy metabolism and participates in multiple biological processes, including lipid metabolism, autophagy, inflammation, and cell apoptosis. Promoting AMPK activation can reduce hepatic lipid accumulation and insulin resistance, alleviate the development of NAFLD, reduce liver inflammation and fibrosis, and inhibit the progression of NAFLD to nonalcoholic steatohepatitis.

Indexed as

Insulin ResistanceNon-alcoholic Fatty Liver DiseaseAMP-Activated Protein KinasesHumansInflammationLipid MetabolismLipidsLiverAMP-Activated Protein KinasesLipidsAMP-dependent protein kinaseGlucose and fat metabolismNonalcoholic fatty liver diseaseNonalcoholic steatohepatitis

Identifiers

PMID38238958
PMCPMC12814285

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.