Evidence map›Paper›PMID 38238739›Full record

ArticleJournal of translational medicine2024

New advances of the androgen receptor in prostate cancer: report from the 1st International Androgen Receptor Symposium.

Sherif Mehralivand, Christian Thomas, Martin Puhr, Frank Claessens, Arjanneke F van de Merbel, Anna Dubrovska, Guido Jenster, Christof Bernemann, Ulrich Sommer, Holger H H Erb

Open access · goldAbstract read
In one paragraph

Article in Journal of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 16 citations in OpenAlex.

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  9. 7,7-Bis(3-Indolyl)-Journal of microbiology and biotechnology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 4 countries.

Sherif MehralivandDepartment of Urology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Christian ThomasDepartment of Urology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.
Martin PuhrDepartment of Urology, Medical University of Innsbruck, Innsbruck, Austria.
Frank ClaessensMolecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Arjanneke F van de MerbelDepartment of Urology, Leiden University Medical Center, Leiden, The Netherlands.
Anna DubrovskaOncoRay-National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden and Helmholtz-Zentrum Dresden-Rossendorf, Dresden, Germany.
Guido JensterDepartment of Urology, Erasmus MC Cancer Institute, University Medical Center, Rotterdam, The Netherlands.
Christof BernemannDepartment of Urology, University Hospital Muenster, Muenster, Germany.
Ulrich SommerInstitut für Pathologie, Medical Faculty, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Holger H H ErbDepartment of Urology, Faculty of Medicine, University Hospital Carl Gustav Carus, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany. holger.erb@uniklinikum-dresden.de.ORCID 0000-0001-5209-7914
University Hospital Carl Gustav Carus · DEGerman Cancer Research Center · DEErasmus MC Cancer Institute · NLInnsbruck Medical University · ATKU Leuven · BELeiden University Medical Center · NLUniversity Hospital Münster · DE

Funding

Astellas Pharma Europe 77259493
6 · The paper itself

Abstract

The androgen receptor (AR) is a crucial player in various aspects of male reproduction and has been associated with the development and progression of prostate cancer (PCa). Therefore, the protein is the linchpin of current PCa therapies. Despite great research efforts, the AR signaling pathway has still not been deciphered, and the emergence of resistance is still the biggest problem in PCa treatment. To discuss the latest developments in AR research, the "1st International Androgen Receptor Symposium" offered a forum for the exchange of clinical and scientific innovations around the role of the AR in prostate cancer (PCa) and to stimulate new collaborative interactions among leading scientists from basic, translational, and clinical research. The symposium included three sessions covering preclinical studies, prognostic and diagnostic biomarkers, and ongoing prostate cancer clinical trials. In addition, a panel discussion about the future direction of androgen deprivation therapy and anti-AR therapy in PCa was conducted. Therefore, the newest insights and developments in therapeutic strategies and biomarkers are discussed in this report.

Indexed as

Prostatic NeoplasmsProstatic Neoplasms, Castration-ResistantAndrogen AntagonistsBiomarkersHumansMaleReceptors, AndrogenSignal TransductionAndrogen AntagonistsBiomarkersReceptors, AndrogenAndrogen deprivation therapyAndrogen receptorNR3C4PCa

Identifiers

PMID38238739
PMCPMC10795409
OpenAlexW4390976151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.