Evidence map›Paper›PMID 38238707›Full record

Trial reportBMC public health2024

Cross-sectional and longitudinal associations between the 24-hour movement behaviours, including muscle and bone strengthening activity, with bone and lean mass from childhood to adolescence.

Annie M Skinner, Alan R Barker, Sarah A Moore, Sonja Soininen, Eero A Haapala, Juuso Väistö, Kate Westgate, Soren Brage, Timo A Lakka, Dimitris Vlachopoulos

Registry-linked trialAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01803776 (The Physical Activity and Nutrition in Children), which is not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01803776 naunknown statusnot on this map

The Physical Activity and Nutrition in Children (PANIC) Study

TypeinterventionalSponsorUniversity of Eastern FinlandRan2007 to 2023Enrolled504ConditionsOverweight, Glucose Metabolism Disorders, Lipid Metabolism Disorders, Blood PressureArmslifestyle counseling
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Annie M SkinnerChildren's Health and Exercise Research Centre, University of Exeter, Exeter, UK.
Alan R BarkerChildren's Health and Exercise Research Centre, University of Exeter, Exeter, UK.
Sarah A MooreSchool of Health and Human Performance, Dalhousie University, Halifax, Canada.
Sonja SoininenInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Eero A HaapalaInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Juuso VäistöInstitute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Kate WestgateMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Soren BrageMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
Timo A Lakka *Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.
Dimitris Vlachopoulos *Children's Health and Exercise Research Centre, University of Exeter, Exeter, UK. D.Vlachopoulos@exeter.ac.uk.

Funding

Medical Research Council MC_UU_00006/4Medical Research Council MC_UU_12015/3
6 · The paper itself

Abstract

backgroundThis study aimed to assess whether moderate-to-vigorous physical activity (MVPA), sport and exercise as a proxy measure of muscle and bone strengthening activity, sedentary behaviour, and sleep were associated with total-body-less-head (TBLH) bone mineral content (BMC) and TBLH lean mass cross-sectionally and longitudinally from age 6 to 9 years and age 9 to 11 years to age 15 to 17 years.

methodsWe used longitudinal data from a population sample of Finnish children from the Physical Activity and Nutrition in Children study (age 6 to 9 years: n = 478, 229 females; age 9 to 11 years: n = 384, 197 females; age 15 to 17 years: n = 222, 103 females). Linear regression analysed the cross-sectional and longitudinal associations between accelerometer-assessed MVPA, sedentary time and sleep, and questionnaire-assessed sport and exercise participation and screen time with dual-energy X-ray absorptiometry-assessed TBLH BMC and lean mass.

resultsIn females, MVPA at age 6 to 9 years was positively associated with TBLH BMC at age 15 to 17 years (β = 0.008, p = 0.010). Sport and exercise at age 9 to 11 years was positively associated with TBLH BMC (β = 0.020, p = 0.002) and lean mass (β = 0.343, p = 0.040) at age 15 to 17 years. MVPA at age 9 to 11 years was positively associated with TBLH lean mass (β = 0.272, p = 0.004) at age 15 to 17 years. In males, sleep at age 6 to 9 years was positively associated with TBLH lean mass (β = 0.382, p = 0.003) at age 15 to 17 years. Sport and exercise at age 9 to 11 years was positively associated with TBLH BMC (β = 0.027, p = 0.012) and lean mass (β = 0.721, p < 0.001) at age 15 to 17 years.

conclusionsPromoting engagement in the 24-hour movement behaviours in childhood, particularly sport and exercise to strengthen muscle and bone, is important in supporting bone and lean mass development in adolescence.

trial registrationNCT01803776; first trial registration date: 04/03/2013.

Indexed as

Bone and BonesBone DensityAbsorptiometry, PhotonAdolescentChildCross-Sectional StudiesExerciseFemaleHumansMaleMusclesAccelerometryBone mineral contentDXAExerciseModerate-to-vigorous physical activityPaediatricsSedentary behaviourSleepSport

Identifiers

PMID38238707
PMCPMC10797891

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.