Evidence map›Paper›PMID 38238599›Full record

Trial reportQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024

The quality of life of frequently vs. infrequently screened HPV vaccinated women.

Kaisa Taavela, Tiina Eriksson, Heini Huhtala, Anne Bly, Katja Harjula, Kaisa Heikkilä, Mari Hokkanen, Mervi Nummela, Laura Kotaniemi-Talonen, Matti Lehtinen and 1 more

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02149030 (Effectiveness of Cervical Screening in HPV Vaccinated Women - a Randomized Trial), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02149030 naactive not recruitingnot on this map

Effectiveness of Cervical Screening in HPV Vaccinated Women - a Randomized Trial

TypeinterventionalSponsorTampere UniversityRan2014 to 2025Enrolled6,958ConditionsCervical Intraepithelial Neoplasia Grade 2/3ArmsCytological screening in A1 and A3
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Kaisa TaavelaFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33014, Tampere, Finland.
Tiina ErikssonFICAN-Mid, Tampere, Finland.
Heini HuhtalaFaculty of Social Sciences, Tampere University, Tampere, Finland.
Anne BlyFICAN-Mid, Tampere, Finland.
Katja HarjulaFICAN-Mid, Tampere, Finland.
Kaisa HeikkiläFICAN-Mid, Tampere, Finland.
Mari HokkanenFICAN-Mid, Tampere, Finland.
Mervi NummelaFICAN-Mid, Tampere, Finland.
Laura Kotaniemi-TalonenFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33014, Tampere, Finland.
Matti LehtinenDepartment of Laboratory Medicine, Karolinska Institute, Stockholm, Sweden.
Karolina LouvantoFaculty of Medicine and Health Technology, Tampere University, Arvo Ylpön Katu 34, 33014, Tampere, Finland. karolina.louvanto@tuni.fi.ORCID http://orcid.org/0000-0002-1172-363X
Tampere University · FIKarolinska Institutet · SETampere University of Applied Sciences · FI

Funding

Suomen Lääketieteen Säätiö 5525Tampere University Hospital Support Foundation MK371
6 · The paper itself

Abstract

purposeCervical lesions caused by human papillomavirus (HPV) are related to decreased quality of life (QoL) of women. Also, cervical cancer (CC) screening can cause psychological adverse effects. It has been assumed that by decreasing the HPV-related disease burden, HPV vaccinations would increase the QoL. This study compares the effect of CC screening on QoL of HPV vaccinated women in two different screening protocols.

methodsA total of 753 HPV16/18 vaccinated women were randomized to frequent (22/25/28 years of age) and infrequent (28 years of age) CC screening arms. QoL questionnaires (EQ VAS, RAND 36, amended CECA 10) were sent at the age of 28.

resultsMedian EQ VAS scores were 80 (Q

conclusionThere was no significant difference in the QoL of HPV vaccinated women between the two CC screening arms. Women were mostly satisfied with the screening experience despite the screening frequency. This information is important for the future screening program planning as we need to reach the best possible balance with screening benefits and harms. TRIAL REGISTRATION NUMBER: NCT02149030, date of registration 29/5/2014.

Indexed as

Papillomavirus InfectionsUterine Cervical NeoplasmsEarly Detection of CancerFemaleHuman papillomavirus 16Human papillomavirus 18Human Papillomavirus VirusesHumansQuality of LifeCervical cancer screeningHPVHPV vaccinationHuman papillomavirusQuality of life

Identifiers

PMID38238599
PMCPMC10973058
OpenAlexW4390967610

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.