Evidence map›Paper›PMID 38238525›Full record

ArticleJournal of the Association for Research in Otolaryngology : JARO2024

An Implantable Piezofilm Middle Ear Microphone: Performance in Human Cadaveric Temporal Bones.

John Z Zhang, Lukas Graf, Annesya Banerjee, Aaron Yeiser, Christopher I McHugh, Ioannis Kymissis, Jeffrey H Lang, Elizabeth S Olson, Hideko Heidi Nakajima

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Association for Research in Otolaryngology : JARO, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. The UmboMic: A PVDF Cantilever Microphone.Journal of micromechanics and microengineering : structures, devices, and systems · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

John Z Zhang *Massachusetts Institute of Technology, Cambridge, USA.
Lukas Graf *Harvard Medical School, Massachusetts Eye and Ear, Boston, USA.
Annesya BanerjeeHarvard Medical School, Massachusetts Eye and Ear, Boston, USA.
Aaron YeiserMassachusetts Institute of Technology, Cambridge, USA.
Christopher I McHughHarvard Medical School, Massachusetts Eye and Ear, Boston, USA.
Ioannis KymissisColumbia University, New York, USA.
Jeffrey H LangMassachusetts Institute of Technology, Cambridge, USA.
Elizabeth S OlsonColumbia University, New York, USA.
Hideko Heidi NakajimaHarvard Medical School, Massachusetts Eye and Ear, Boston, USA. heidi_nakajima@meei.harvard.edu.ORCID http://orcid.org/0000-0002-1377-1934
Massachusetts Eye and Ear Infirmary · USMassachusetts Institute of Technology · USColumbia University · US

Funding

Implantable Microphones for Fully Implantable Hearing ProstheticsR01DC016874 · NIDCD · MASSACHUSETTS EYE AND EAR INFIRMARY · PI LANG, JEFFREY H, NAKAJIMA, HIDEKO HEIDI · 2019 to 2023
$1.8M
NIDCD NIH HHS R01 DC016874
6 · The paper itself

Abstract

purposeOne of the major reasons that totally implantable cochlear microphones are not readily available is the lack of good implantable microphones. An implantable microphone has the potential to provide a range of benefits over external microphones for cochlear implant users including the filtering ability of the outer ear, cosmetics, and usability in all situations. This paper presents results from experiments in human cadaveric ears of a piezofilm microphone concept under development as a possible component of a future implantable microphone system for use with cochlear implants. This microphone is referred to here as a drum microphone (DrumMic) that senses the robust and predictable motion of the umbo, the tip of the malleus.

methodsThe performance was measured by five DrumMics inserted in four different human cadaveric temporal bones. Sensitivity, linearity, bandwidth, and equivalent input noise were measured during these experiments using a sound stimulus and measurement setup.

resultsThe sensitivity of the DrumMics was found to be tightly clustered across different microphones and ears despite differences in umbo and middle ear anatomy. The DrumMics were shown to behave linearly across a large dynamic range (46 dB SPL to 100 dB SPL) across a wide bandwidth (100 Hz to 8 kHz). The equivalent input noise (over a bandwidth of 0.1-10 kHz) of the DrumMic and amplifier referenced to the ear canal was measured to be about 54 dB SPL in the temporal bone experiment and estimated to be 46 dB SPL after accounting for the pressure gain of the outer ear.

conclusionThe results demonstrate that the DrumMic behaves robustly across ears and fabrication. The equivalent input noise performance (related to the lowest level of sound measurable) was shown to approach that of commercial hearing aid microphones. To advance this demonstration of the DrumMic concept to a future prototype implantable in humans, work on encapsulation, biocompatibility, and connectorization will be required.

Indexed as

Cochlear ImplantationCochlear ImplantsCadaverEar CanalEar, MiddleHumansCochlear implantImplantableImplantable microphoneMicrophonePiezofilm

Identifiers

PMID38238525
PMCPMC10907555
OpenAlexW4390986852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.