ArticleNature neuroscience2024
Microglia regulate sleep through calcium-dependent modulation of norepinephrine transmission.
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Article in Nature neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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0cells of the map it votes in
57citing papers in PubMed
24.3field-weighted citation impact, top 1% of its field
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
57 citing papers in PubMed, 100 citations in OpenAlex.
- Losing sleep over glia: new mechanisms for Alzheimer-related sleep disruption.Nature reviews. Neurology · 2026Article
- Differential effects of P2Y12 inhibition on sleep and glymphatic function in male and female mice.Brain, behavior, & immunity - health · 2026Article
- Sex-specific role of microglia in ΔNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Microglia stabilize sleep homeostasis via adenosine AScience advances · 2026Article
- Microglia respond to and induce anxiety and grooming in mice using calcium signaling.Molecular psychiatry · 2026Article
- The sleep-wake cycle: molecular mechanisms, disorders, and therapeutic targets in the context of energy metabolism.Signal transduction and targeted therapy · 2026Review
- Illuminating the Future of Catecholamine Detection.Journal of neurochemistry · 2026Review
- Auditory Stimulation of Slow-Wave Sleep Promotes Recovery after Brain Injury in an Animal Model.Annals of neurology · 2026Article
- Astrocyte-to-microglia purinergic signaling mediates synaptic shielding and promotes neuronal activity.bioRxiv : the preprint server for biology · 2026Article
- Sleep-circadian modulation of autophagy and glymphatic function: failure of coordinated brain clearance in Parkinson's disease.NPJ Parkinson's disease · 2026Review
- Early microglial response to amyloid plaques drives sleep loss in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Microglia in systemic neuroimmune communication: functions beyond phagocytosis.Trends in immunology · 2026Review
- A neuron-glia circuit anticipates hypoxia to regulate organismal oxygen use.bioRxiv : the preprint server for biology · 2026Article
- Chemogenetic modulation of CNS pericytes: Impact on pericyte CaMolecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Mesoscale Recovery of Microglial and Neuronal Dynamics After Craniotomy Across Wide Cortex in Transgenic Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- The axon initial segment-associated microglia regulate neuronal activity and visual perception.Cell research · 2026Article
- Aurka-Bhlhe41 axis prevents premature aging-like microglial dysfunction and promotes remyelination.Nature communications · 2026Article
- Article
- Astrocyte-induced internal state transitions reshape brainwide sensory, integrative, and motor computations.bioRxiv : the preprint server for biology · 2026Article
- Single-Cell eQTL Revealing Brain Cell-Type-Specific Genetic Control of Insomnia.Journal of molecular neuroscience : MN · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 5 institutions in 2 countries.
Chenyan Ma *Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.
Bing Li *Division of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-8949-733X
Daniel SilvermanDivision of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-3502-3742
Xinlu DingDivision of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.
Anan LiBiomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0002-5877-4813
Chi XiaoKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou, China.
Ganghua HuangKey Laboratory of Biomedical Engineering of Hainan Province, School of Biomedical Engineering, Hainan University, Haikou, China.
Kurtresha WordenDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-5621-7979
Sandra MuroyDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-4014-5189
Wei ChenDepartment of Physics, University of California, Berkeley, Berkeley, CA, USA.
Zhengchao XuBiomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China.
Chak Foon TsoDivision of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.
Yixuan HuangDivision of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0009-0000-4199-9795
Yufan ZhangDivision of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0009-0003-4708-7916
Qingming LuoBiomedical Photonics, Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan, China.ORCID http://orcid.org/0000-0002-6725-9311
Kaoru SaijoDivision of Immunology and Pathogenesis, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0003-1656-1753
Yang DanDivision of Neurobiology, Department of Molecular and Cell Biology, Helen Wills Neuroscience Institute, Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA, USA. ydan@berkeley.edu.ORCID http://orcid.org/0000-0002-3818-877X
Howard Hughes Medical Institute · USUniversity of California, Berkeley · USChinese Academy of Medical Sciences & Peking Union Medical College · CNHainan University · CNWuhan National Laboratory for Optoelectronics · CN
Funding
Immunology & Pathogenesis Program Training GrantT32AI100829 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Gregory M Barton, ELLEN A ROBEY · 2012 to 2026
$4.7MNIAID NIH HHS T32 AI100829
Abstract
Sleep interacts reciprocally with immune system activity, but its specific relationship with microglia-the resident immune cells in the brain-remains poorly understood. Here, we show in mice that microglia can regulate sleep through a mechanism involving G
Indexed as
CalciumMicrogliaAnimalsMiceNorepinephrineSignal TransductionSleepCalciumNorepinephrine
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.