Evidence map›Paper›PMID 38238355›Full record

ArticleScientific reports2024

Exploration of photoprotective and antibiotic activity of wild Polypodiaceae ferns from Costa Rica.

Yaclyn Salazar-Chacón, Maria José Gutierrez-Bolaños, Jimena Padilla-Cordero, Camilo Vidaurre-Rodriguez, Yendry Carvajal-Miranda, Alexander Rojas-Alvarado, Jorengeth Abad Rodríguez-Rodríguez, Gerardo Rodríguez-Rodríguez, Víctor Álvarez-Valverde, Pablo Jiménez-Bonilla

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Aspen PlusAntioxidants (Basel, Switzerland) · 2026
    Article
  2. Phenolic compounds in species of the Blechnaceae.Plant biology (Stuttgart, Germany) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yaclyn Salazar-ChacónLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Maria José Gutierrez-BolañosLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Jimena Padilla-CorderoLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Camilo Vidaurre-RodriguezLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Yendry Carvajal-MirandaLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Alexander Rojas-AlvaradoUniversidad Nacional de Costa Rica, Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Jorengeth Abad Rodríguez-RodríguezLaboratorio de Biotecnología Microbiana (LABIMI), Escuela de Ciencias Biológicas, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Gerardo Rodríguez-RodríguezLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica.
Víctor Álvarez-ValverdeLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica. victor.alvarez.valverde@una.cr.
Pablo Jiménez-BonillaLaboratorio de Fitoquímica (LAFIT), Escuela de Química, Universidad Nacional (UNA), Campus Omar Dengo, Heredia, 83-3000, Costa Rica. pablo.jimenez.bonilla@una.cr.

Funding

International Training in Environmental Health over the LifespanD43TW011403 · FIC · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CLAUDIO, LUZ · 2020 to 2024
$1.3M
FIC NIH HHS D43 TW011403
6 · The paper itself

Abstract

Skin disorders affect millions of people all over the world. There are limited options to treat dermal illnesses such as vitiligo, psoriasis, and atopic dermatitis (eczema). Central American ferns are a potential source of bioactive metabolites against those diseases. Currently, Polypodium leucotomos Poir. is the only one being commercially utilized for this purpose. In this work, we evaluated the concentration of the skin bioactive compounds: quinic and chlorogenic acid, in the extract of 20 wild ferns from Costa Rica. We also evaluated the antimicrobial capabilities of the crude extracts of wild ferns and the sun protection factor (SPF) of the extracts. We found 19 out of 20 have either an important concentration of the compounds mentioned above or antimicrobial properties. Also, most samples result in higher SPF than P. aureum's rhizome. We also have studied the fern acclimatization, at different shading conditions, finding a significant influence of the culturing conditions on metabolite production. After acclimatization. So far, we demonstrate that various ferns included in this study are a potential source of treatments for skin conditions.

Indexed as

FernsPolypodiaceaePolypodiumVitiligoAnti-Bacterial AgentsCosta RicaHumansPlant ExtractsAnti-Bacterial AgentsPlant Extracts

Identifiers

PMID38238355
PMCPMC10796928

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.