ArticleCell genomics2024
Karyotypic stasis and swarming influenced the evolution of viral tolerance in a species-rich bat radiation.
Article in Cell genomics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Article
- Article
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- Mutation rate estimate and population genomic analysis reveals decline of koalas prior to human arrival.Molecular biology and evolution · 2026Article
- Comparative Genomics Reveals the Ancestral Recombination Landscape of Placental Mammals.bioRxiv : the preprint server for biology · 2026Article
- Hybridization and Immunology in Animals: A Review.Ecology and evolution · 2026Review
- Evolutionary history of Chinese cavefishes parallels paleogeoclimatic and river capture processes.Communications biology · 2026Article
- A holistic survey of small mammal diversity across an iconic Madrean Sky Island (Santa Catalina Mountains, Arizona, USA).bioRxiv : the preprint server for biology · 2026Article
- Extraordinary diversity of antiviral immune-related gene families across 38 bat species.BMC biology · 2026Article
- The genome sequence of Geoffroy's Bat,Wellcome open research · 2026Article
- Article
- Introgression across Narrow Contact Zones Shapes the Genomic Landscape of Phylogenetic Variation in an African Bird Clade.Systematic biology · 2025Article
- How many mammal species are there now? Updates and trends in taxonomic, nomenclatural, and geographic knowledge.Journal of mammalogy · 2025Article
- Extensive longevity and DNA virus-driven adaptation in nearcticbioRxiv : the preprint server for biology · 2025Article
- Diverse hosts, diverse immune systems: Evolutionary variation in bat immunology.Annals of the New York Academy of Sciences · 2025Review
- Comparative genomics provides insights into chromosomal evolution and immunological adaptation in horseshoe bats.Nature ecology & evolution · 2025Article
- The Genomic Landscape, Causes, and Consequences of Extensive Phylogenomic Discordance in Murine Rodents.Genome biology and evolution · 2025Article
- Distinct Genes with Similar Functions Underlie Convergent Evolution in Myotis Bat Ecomorphs.Molecular biology and evolution · 2024Article
- Signals of positive selection in genomes of palearctic Myotis-bats coexisting with a fungal pathogen.BMC genomics · 2024Article
- Phylogenomic analyses unraveled the evolution of viral tolerance in bats.Cell genomics · 2024Article
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8 authors.
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Abstract
The emergence of COVID-19 and severe acute respiratory syndrome (SARS) has prioritized understanding bats' viral tolerance. Myotis bats are exceptionally species rich and have evolved viral tolerance. They also exhibit swarming, a cryptic behavior where large, multi-species assemblages gather for mating, which has been hypothesized to promote interspecific hybridization. To resolve the coevolution of genome architecture and their unusual antiviral tolerance, we undertook a phylogenomic analysis of 60 Old World Myotis genomes. We demonstrate an extensive history of introgressive hybridization that has replaced the species phylogeny across 17%-93% of the genome except for pericentromeric regions of macrochromosomes. Introgression tracts were enriched on microchromosome regions containing key antiviral pathway genes overexpressed during viral challenge experiments. Together, these results suggest that the unusual Myotis karyotype may have evolved to selectively position immune-related genes in high recombining genomic regions prone to introgression of divergent alleles, including a diversity of interleukin loci responsible for the release of pro-inflammatory cytokines.
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