Evidence map›Paper›PMID 38237203›Full record

ArticleJournal of critical care2024

Implementing an ICU registry in Ethiopia-Implications for critical care quality improvement.

Menbeu Sultan, Ayalew Zewdie, Dilanthi Priyadarshani, Ephrem Hassen, Melkamu Tilahun, Tigist Geremew, Abi Beane, Rashan Haniffa, Sean M Berenholtz, William Checkley and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Menbeu SultanSt. Paul's Hospital Millennium Medical Center, Addis Ababa, Ethiopia.
Ayalew ZewdieSt. Paul's Hospital Millennium Medical Center, Addis Ababa, Ethiopia; Addis Ababa Burn, Emergency and Trauma Hospital, Addis Ababa, Ethiopia.
Dilanthi PriyadarshaniNetwork for Improving Critical Care Systems and Training, Colombo, Sri Lanka. Electronic address: dilanthi@nicslk.com.
Ephrem HassenSt. Paul's Hospital Millennium Medical Center, Addis Ababa, Ethiopia.
Melkamu TilahunSt. Paul's Hospital Millennium Medical Center, Addis Ababa, Ethiopia.
Tigist GeremewAddis Ababa Burn, Emergency and Trauma Hospital, Addis Ababa, Ethiopia.
Abi BeaneCentre for Inflammation Research, University of Edinburgh, Scotland, UK. Electronic address: abi@nicslk.com.
Rashan HaniffaCentre for Inflammation Research, University of Edinburgh, Scotland, UK. Electronic address: rashan@nicslk.com.
Sean M BerenholtzJohns Hopkins University School of Medicine, Department of Anesthesia and Critical Care Medicine, Baltimore, MD, USA. Electronic address: sberenho@jhmi.edu.
William CheckleyJohns Hopkins University School of Medicine, Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Baltimore, MD, USA. Electronic address: wcheck1@jhmi.edu.
Bhakti HansotiJohns Hopkins University School of Medicine, Department of Emergency Medicine, Baltimore, MD, USA. Electronic address: bhansot1@jhmi.edu.
Adam D LaytinJohns Hopkins University School of Medicine, Department of Anesthesia and Critical Care Medicine, Baltimore, MD, USA; Johns Hopkins University School of Medicine, Department of Emergency Medicine, Baltimore, MD, USA. Electronic address: alaytin1@jhmi.edu.

Funding

Medical Research Council MR/V030884/1Wellcome Trust
6 · The paper itself

Abstract

purposeIntensive care units (ICUs) in low- and middle-income countries have high mortality rates, and clinical data are needed to guide quality improvement (QI) efforts. This study utilizes data from a validated ICU registry specially developed for resource-limited settings to identify evidence-based QI priorities for ICUs in Ethiopia. MATERIALS AND

methodsA retrospective cohort analysis of data from two tertiary referral hospital ICUs in Addis Ababa, Ethiopia from July 2021-June 2022 was conducted to describe casemix, complications and outcomes and identify features associated with ICU mortality.

resultsAmong 496 patients, ICU mortality was 35.3%. The most common reasons for ICU admission were respiratory failure (24.0%), major head injury (17.5%) and sepsis/septic shock (13.3%). Complications occurred in 41.0% of patients. ICU mortality was higher among patients with respiratory failure (46.2%), sepsis (66.7%) and vasopressor requirements (70.5%), those admitted from the hospital ward (64.7%), and those experiencing major complications in the ICU (62.3%).

conclusionsIn this study, ICU mortality was high, and complications were common and associated with increased mortality. ICU registries are invaluable tools to understand local casemix and clinical outcomes, especially in resource-limited settings. These findings provide a foundation for QI efforts and a baseline to evaluate their impact.

Indexed as

Respiratory InsufficiencySepsisShock, SepticCritical CareEthiopiaHospital MortalityHumansIntensive Care UnitsQuality ImprovementRegistriesRetrospective StudiesAfricaComplicationsCritical careICU registryIntensive care unitLow- and middle-income countriesOutcomes researchQuality improvementResource-limited setting

Identifiers

PMID38237203
PMCPMC10996997

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.