Evidence map›Paper›PMID 38236918›Full record

ArticlePloS one2024

Coordinating virus research: The Virus Infectious Disease Ontology.

John Beverley, Shane Babcock, Gustavo Carvalho, Lindsay G Cowell, Sebastian Duesing, Yongqun He, Regina Hurley, Eric Merrell, Richard H Scheuermann, Barry Smith

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

John BeverleyDepartment of Philosophy, University at Buffalo, Buffalo, NY, United States of America.ORCID 0000-0002-1118-1738
Shane BabcockNational Center for Ontological Research, Buffalo, NY, United States of America.
Gustavo CarvalhoDepartment of Cognitive Science, Northwestern University, Evanston, IL, United States of America.
Lindsay G CowellDepartment of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, United States of America.
Sebastian DuesingDepartment of Philosophy, Loyola University, Chicago, IL, United States of America.
Yongqun HeComputational Medicine and Bioinformatics, University of Michigan Medical School, He Group, Ann Arbor, MI, United States of America.
Regina HurleyNational Center for Ontological Research, Buffalo, NY, United States of America.
Eric MerrellDepartment of Philosophy, University at Buffalo, Buffalo, NY, United States of America.
Richard H ScheuermannDepartment of Informatics, J. Craig Venter Institute, La Jolla, CA, United States of America.
Barry SmithDepartment of Philosophy, University at Buffalo, Buffalo, NY, United States of America.
University at Buffalo, State University of New York · USNorthwestern University · USJ. Craig Venter Institute · USLoyola University Chicago · USThe University of Texas Southwestern Medical Center · USUniversity of Michigan · USWright-Patterson Air Force Base · US

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
NCATS NIH HHS UL1 TR001412
6 · The paper itself

Abstract

The COVID-19 pandemic prompted immense work on the investigation of the SARS-CoV-2 virus. Rapid, accurate, and consistent interpretation of generated data is thereby of fundamental concern. Ontologies-structured, controlled, vocabularies-are designed to support consistency of interpretation, and thereby to prevent the development of data silos. This paper describes how ontologies are serving this purpose in the COVID-19 research domain, by following principles of the Open Biological and Biomedical Ontology (OBO) Foundry and by reusing existing ontologies such as the Infectious Disease Ontology (IDO) Core, which provides terminological content common to investigations of all infectious diseases. We report here on the development of an IDO extension, the Virus Infectious Disease Ontology (VIDO), a reference ontology covering viral infectious diseases. We motivate term and definition choices, showcase reuse of terms from existing OBO ontologies, illustrate how ontological decisions were motivated by relevant life science research, and connect VIDO to the Coronavirus Infectious Disease Ontology (CIDO). We next use terms from these ontologies to annotate selections from life science research on SARS-CoV-2, highlighting how ontologies employing a common upper-level vocabulary may be seamlessly interwoven. Finally, we outline future work, including bacteria and fungus infectious disease reference ontologies currently under development, then cite uses of VIDO and CIDO in host-pathogen data analytics, electronic health record annotation, and ontology conflict-resolution projects.

Indexed as

Biological OntologiesCommunicable DiseasesCOVID-19Virus DiseasesHumansPandemicsVocabulary, Controlled

Identifiers

PMID38236918
PMCPMC10796065
OpenAlexW4390970105

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.