ReviewPLOS digital health2024
Peer review of GPT-4 technical report and systems card.
Review in PLOS digital health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The TRIPOD-LLM reporting guideline for studies using large language models: a Korean translation.Ewha medical journal · 2025Guideline
- Navigating the Prescription Drug Information System.Clinical pharmacology and therapeutics · 2026Review
- Concordance between GPT-4 and a multidisciplinary tumor board in pancreatic cancer: A prospective pilot study.Langenbeck's archives of surgery · 2026Observational
- Discordance Between Textual Reasoning and Visual Interpretation in Large Language Models for Low Back Pain: Cross-Sectional Quantitative Evaluation and Exploratory Multimodal Stress Test.JMIR medical informatics · 2026Article
- Evaluating guideline adherence in LLM studies using LLMs.Japanese journal of radiology · 2026Article
- Adapting general representations of pretrained vision foundation models to seismic understanding.Communications engineering · 2026Article
- Comparing regular expression and machine learning approaches to predict immigrant status from primary care electronic medical record data in Ontario, Canada.PLOS digital health · 2026Article
- TrialMatchAI: an end-to-end AI-powered clinical trial recommendation system to streamline patient-to-trial matching.Nature communications · 2026Article
- Integration of fairness-awareness into clinical language processing models.Communications medicine · 2026Article
- Patient address parsing via KG-aware contrastive learning and constrained on-prem LLM inference.Scientific reports · 2026Article
- Beyond writing machines: A Kano model analysis of researchers' hierarchical needs for AIGC services across the research lifecycle.PloS one · 2026Article
- Evaluation of large language models for nursing support in maternal venous thromboembolism care.Frontiers in public health · 2026Article
- A review for navigating the trade-offs: evaluating open-source and proprietary large language models for clinical and biomedical information extraction.Frontiers in digital health · 2026Review
- Using generative artificial intelligence in clinical practice: a narrative review and proposed agenda for implementation.The Medical journal of Australia · 2025Review
- SciDaSynth: Interactive Structured Data Extraction From Scientific Literature With Large Language Model.Campbell systematic reviews · 2025Article
- Article
- Readability, reliability, and quality of nursing care plan texts generated by ChatGPT.BMC nursing · 2025Article
- Dr. LLM Will See You Now: The Ability of ChatGPT to Provide Geographically Tailored Colorectal Cancer Screening and Surveillance Recommendations.Journal of clinical medicine · 2025Article
- A Review of the Opportunities and Challenges with Large Language Models in Radiology: The Road Ahead.AJNR. American journal of neuroradiology · 2025Review
- Research Progress on Data-Driven Industrial Fault Diagnosis Methods.Sensors (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
The study provides a comprehensive review of OpenAI's Generative Pre-trained Transformer 4 (GPT-4) technical report, with an emphasis on applications in high-risk settings like healthcare. A diverse team, including experts in artificial intelligence (AI), natural language processing, public health, law, policy, social science, healthcare research, and bioethics, analyzed the report against established peer review guidelines. The GPT-4 report shows a significant commitment to transparent AI research, particularly in creating a systems card for risk assessment and mitigation. However, it reveals limitations such as restricted access to training data, inadequate confidence and uncertainty estimations, and concerns over privacy and intellectual property rights. Key strengths identified include the considerable time and economic investment in transparent AI research and the creation of a comprehensive systems card. On the other hand, the lack of clarity in training processes and data raises concerns about encoded biases and interests in GPT-4. The report also lacks confidence and uncertainty estimations, crucial in high-risk areas like healthcare, and fails to address potential privacy and intellectual property issues. Furthermore, this study emphasizes the need for diverse, global involvement in developing and evaluating large language models (LLMs) to ensure broad societal benefits and mitigate risks. The paper presents recommendations such as improving data transparency, developing accountability frameworks, establishing confidence standards for LLM outputs in high-risk settings, and enhancing industry research review processes. It concludes that while GPT-4's report is a step towards open discussions on LLMs, more extensive interdisciplinary reviews are essential for addressing bias, harm, and risk concerns, especially in high-risk domains. The review aims to expand the understanding of LLMs in general and highlights the need for new reflection forms on how LLMs are reviewed, the data required for effective evaluation, and addressing critical issues like bias and risk.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.