ArticlePLoS pathogens2024
The soil-borne white root rot pathogen Rosellinia necatrix expresses antimicrobial proteins during host colonization.
Article in PLoS pathogens, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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Who cites it
13 citing papers in PubMed, 26 citations in OpenAlex.
- Plant-associated fungi co-opt ancient antimicrobials for host manipulation.Science advances · 2026Article
- Differential contributions of an antimicrobial effector from Verticillium dahliae to virulence and tomato microbiota assembly across natural soils.Microbiome · 2026Article
- An antifungal effector from a plant-parasitic nematode modulates host fungal community composition and supports ecological fitness.NPJ biofilms and microbiomes · 2026Article
- Article
- Undermining the cry for help: the phytopathogenic fungus Verticillium dahliae secretes an antimicrobial effector protein to undermine host recruitment of antagonistic Pseudomonas bacteria.The New phytologist · 2026Article
- Rootstock genetic background in almond cultivation influences the composition of root-associated microbial communities and enrichment of taxa associated with plant defense and nutrient availability.BMC plant biology · 2025Article
- Inhibition of RNase to Attenuate Fungal-Manipulated Rhizosphere Microbiome and Diseases.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Avocado rhizosphere community profiling: white root rot and its impact on microbial composition.Frontiers in microbiology · 2025Article
- The impact of filamentous plant pathogens on the host microbiota.BMC biology · 2024Review
- Fusaric acid mediates the assembly of disease-suppressive rhizosphere microbiota via induced shifts in plant root exudates.Nature communications · 2024Article
- Complete mitochondrial genome sequence of the white root rot pathogenMitochondrial DNA. Part B, Resources · 2024Article
- Evaluation of Soil Antagonism against the White Root Rot Fungus Rosellinia necatrix and Pathogen Mycosphere Communities in Biochar-amended Soil.Microbes and environments · 2024Article
- Co-evolution within the plant holobiont drives host performance.EMBO reports · 2023Review
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
Abstract
Rosellinia necatrix is a prevalent soil-borne plant-pathogenic fungus that is the causal agent of white root rot disease in a broad range of host plants. The limited availability of genomic resources for R. necatrix has complicated a thorough understanding of its infection biology. Here, we sequenced nine R. necatrix strains with Oxford Nanopore sequencing technology, and with DNA proximity ligation we generated a gapless assembly of one of the genomes into ten chromosomes. Whereas many filamentous pathogens display a so-called two-speed genome with more dynamic and more conserved compartments, the R. necatrix genome does not display such genome compartmentalization. It has recently been proposed that fungal plant pathogens may employ effectors with antimicrobial activity to manipulate the host microbiota to promote infection. In the predicted secretome of R. necatrix, 26 putative antimicrobial effector proteins were identified, nine of which are expressed during plant colonization. Two of the candidates were tested, both of which were found to possess selective antimicrobial activity. Intriguingly, some of the inhibited bacteria are antagonists of R. necatrix growth in vitro and can alleviate R. necatrix infection on cotton plants. Collectively, our data show that R. necatrix encodes antimicrobials that are expressed during host colonization and that may contribute to modulation of host-associated microbiota to stimulate disease development.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.