Evidence map›Paper›PMID 38236729›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Bacterial flagella hijack type IV pili proteins to control motility.

Xiaolin Liu, Shoichi Tachiyama, Xiaotian Zhou, Rommel A Mathias, Sharmin Q Bonny, Mohammad F Khan, Yue Xin, Anna Roujeinikova, Jun Liu, Karen M Ottemann

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Characterization ofJournal of bacteriology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The ancient E-ring in bacterial flagellar motors.FEMS microbiology reviews · 2026
    Review
  8. Article
  9. Article
  10. Pathogenicity ofWorld journal of clinical oncology · 2025
    Review
  11. Article
  12. Review
  13. FlgY, PflA, and PflB form a spoke-ring network in the high-torque flagellar motor ofProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Journal of bacteriology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Xiaolin Liu *Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064.ORCID 0000-0001-5891-4559
Shoichi Tachiyama *Department of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT 06536.ORCID 0000-0003-2010-212X
Xiaotian ZhouInfection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Rommel A MathiasInfection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Sharmin Q BonnyInfection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Mohammad F KhanInfection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.ORCID 0000-0002-6373-7021
Yue XinInfection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Anna RoujeinikovaInfection and Immunity Program, Department of Microbiology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.ORCID 0000-0001-8478-4751
Jun LiuDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, CT 06536.ORCID 0000-0003-3108-6735
Karen M OttemannDepartment of Microbiology and Environmental Toxicology, University of California, Santa Cruz, CA 95064.ORCID 0000-0001-6265-7401
Australian Regenerative Medicine Institute · AUUniversity of California, Santa Cruz · USYale University · US

Funding

The function of chemotactic signal transduction during colonization and diseaseR01AI116946 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI OTTEMANN, KAREN M · 2016 to 2025
$5.1M
Regulation of Host Innate Immunity Against Viral InfectionR01AI087846 · NIAID · UNIVERSITY OF CHICAGO · PI GACK, MICHAELA ULRIKE · 2010 to 2020
$3.9M
Roles for Motility in Helicobactor pylori pathogenesisR01AI050000 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI OTTEMANN, KAREN M · 2002 to 2011
$3.6M
Delineation of unique flagellar proteins in spirochetesR01AI132818 · NIAID · EAST CAROLINA UNIVERSITY · PI Jun Liu, MD A MOTALEB · 2018 to 2026
$3.3M
Understanding and manipulating chronic Helicobacter pylori to enhance treatmentR01AI164682 · NIAID · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI OTTEMANN, KAREN M · 2021 to 2025
$2.0M
NIAID NIH HHS R01 AI050000NIAID NIH HHS R01 AI087846NIAID NIH HHS R01 AI116946NIAID NIH HHS R01 AI132818NIAID NIH HHS R01 AI164682
6 · The paper itself

Abstract

Bacterial flagella and type IV pili (TFP) are surface appendages that enable motility and mechanosensing through distinct mechanisms. These structures were previously thought to have no components in common. Here, we report that TFP and some flagella share proteins PilO, PilN, and PilM, which we identified as part of the

Indexed as

Bacterial ProteinsFimbriae, BacterialBacteriaFlagellaBacterial Proteinsflagellar motormechanoresponsenanomachine

Identifiers

PMID38236729
PMCPMC10823254
OpenAlexW4390986558

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.