SynthesisJournal of global health2024
Syphilis epidemic among men who have sex with men: A global systematic review and meta-analysis of prevalence, incidence, and associated factors.
Synthesis in Journal of global health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Association between asthma, allergic rhinitis, atopic dermatitis, and dental caries: evidence from systematic review with meta-analysis and Mendelian randomisation investigation.Journal of global health · 2026Pooled it
- Patterns and Clinical Efficacy of Biologics Switching in Patients With Severe Asthma: A Systematic Review and Meta-Analysis.Allergy · 2026Pooled it
- Prevalence, incidence and risk factors of syphilis among men who have sex with men in China from 2013 to 2025: a systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Review
- Increasing Syphilis Prevalence Among MSM Across India Despite Improvements in the HIV Care Continuum.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Syphilis Diagnosis and Interest in Doxycycline Postexposure Prophylaxis Among Young Black Sexual and Gender Minorities.Open forum infectious diseases · 2026Article
- Incidence, recurrence, and determinants of sexually transmitted infections among people with HIV: a multicenter cohort study in China, 2010-2024, with implications for integrated HIV-STI prevention across the Western Pacific.The Lancet regional health. Western Pacific · 2026Article
- Spatiotemporal heterogeneity and multiscale social influencing factors of syphilis in the mainland of China, 2005-2022.iScience · 2026Article
- Evaluation of the service quality and diagnostic performance of syphilis self-test kits purchased from E-commerce platforms in China.Scientific reports · 2026Article
- Prevalence of chlamydial, gonococcal and syphilis positivity by anatomical site and sex via self-collected biospecimens using at-home testing kits among a large and diverse cohort of men and women enrolled in the MACS/WIHS Combined Cohort Study (MWCCS) in the USA.Sexually transmitted infections · 2026Article
- Technological innovations and breakthrough pathways in syphilis diagnosis: addressing global resurgence and the journey toward elimination.Frontiers in cellular and infection microbiology · 2026Review
- Trend in the detection rate of syphilis among older adults: time series analysis, Brazil, 2014-2023.Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil · 2026Article
- Decreasing trends of syphilis among people with HIV at a university hospital before implementation of doxycycline prophylaxis for syphilis: implications for targeted syphilis prevention.Sexually transmitted infections · 2025Article
- Factors associated with active syphilis infection in US blood donors.Transfusion · 2025Article
- Intersecting Risk Factors Associated With High Syphilis Seroprevalence Among a Street-Involved Population in Canada.Open forum infectious diseases · 2025Article
- Willingness to accept Doxycycline post-exposure prophylaxis for bacterial stis prevention among men who have sex with men in Southern China: a cross-sectional analysis.BMC infectious diseases · 2025Article
- Population Prevalence and Correlates of Syphilis in Rural, Southwestern Uganda.Open forum infectious diseases · 2025Article
- Malignant Syphilis Mimicking Lymphoma in HIV: A Challenging Case and a Review of Literature Focusing on the Role of HIV and Syphilis Coinfection.Microorganisms · 2025Review
- Clinical and imaging findings of neurosyphilis.Frontiers in neurology · 2025Article
- Treponema pallidum infection in asymptomatic persons: A puzzling scenario in the Canary Islands (Spain) (2001-2020).PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: We aimed to estimate the prevalence and incidence of syphilis at global, regional and national levels for human immunodeficiency virus (HIV)-positive and HIV-negative men who have sex with men (MSM) and explore the association between demographic and social behavioural factors and syphilis infection. Methods: We searched PubMed, Embase, and the Cochrane Library from 1 January 2012 to 31 December 2022 for studies of reported crude syphilis prevalence or incidence in MSM or with sufficient data to calculate prevalence or incidence rate in MSM. Results: We included 376 articles reporting on 409 records from 62 countries to calculate syphilis prevalence and incidence in MSM. The pooled prevalence of syphilis in MSM was 10.4%, with substantial differences between countries and regions. Syphilis prevalence was substantially higher in HIV-positive than in HIV-negative MSM. The pooled incidence of syphilis in MSM was 76.4 per 1000 person-years. Older age, lower education, nitrite or recreational drug use, group sex, and multiple sexual partners were identified as risk factors for syphilis infection. Conclusions: A disproportionate geographic pattern of syphilis infection in MSM and significant threats of syphilis infection were revealed. The 'hidden risk' in specific regions and the inadequately elucidated drivers of high-risk behaviours, need to be fully acknowledged and addressed. Registration: PROSPERO: CRD42023422218.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.