Evidence map›Paper›PMID 38236393›Full record

ArticleAnalytical and bioanalytical chemistry2024

Optical fiber surface plasmon resonance sensor using electroless-plated gold film for thrombin detection.

Yu Huang, Xiaoyin Pu, Husun Qian, Chin-Jung Chuang, Shanshan Dong, Jiangling Wu, Jianjiang Xue, Wei Cheng, Shijia Ding, Shengqiang Li

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Yu Huang *Chongqing Key Laboratory of Multi-scale Manufacturing Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, 400714, China. huangyu@cigit.ac.cn.
Xiaoyin Pu *Chongqing Key Laboratory of Multi-scale Manufacturing Technology, Chongqing Institute of Green and Intelligent Technology, Chinese Academy of Sciences, Chongqing, 400714, China.
Husun QianDepartment of Laboratory Medicine, The Affiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China.
Chin-Jung ChuangDepartment of Opto-Electronic Engineering, National Dong Hwa University, Hualien, 97401, Taiwan, China.
Shanshan DongDepartment of Clinical Laboratory, Medical Sciences Research Center, University-Town Hospital of Chongqing Medical University, Chongqing, 401331, China.
Jiangling WuDepartment of Clinical Laboratory, Medical Sciences Research Center, University-Town Hospital of Chongqing Medical University, Chongqing, 401331, China. wujiangling@hospital.cqmu.edu.cn.
Jianjiang XueDepartment of Clinical Laboratory, Medical Sciences Research Center, University-Town Hospital of Chongqing Medical University, Chongqing, 401331, China.
Wei ChengThe Center for Clinical Molecular Medical Detection, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Shijia DingKey Laboratory of Clinical Laboratory Diagnostics (Ministry of Education), College of Laboratory Medicine, Chongqing Medical University, Chongqing, 400016, China.
Shengqiang LiClinical Laboratory, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300000, China. yixuelishengqiang@126.com.
Chongqing Medical University · CNChongqing Institute of Green and Intelligent Technology · CNFirst Teaching Hospital of Tianjin University of Traditional Chinese Medicine · CNGuiyang Medical University · CNNational Dong Hwa University · TW

Funding

Chongqing Municipal Education Commission KJQN202200431Natural Science Foundation of Chongqing Municipality CSTB2023NSCQ-MSX0175Natural Science Foundation of Chongqing Municipality cstc2020jcyj-msxmX0792Venture and Innovation Support Program for Chongqing Overseas Returnees cx2023030
6 · The paper itself

Abstract

This paper describes the simple and label-free detection of thrombin using optical fiber surface plasmon resonance (SPR) sensors based on gold films prepared by the cost-effective method of electroless plating. The plating conditions for simultaneously obtaining gold film on cylindrical core and end surfaces of an optical fiber suitable for measurement were optimized. The fabricated sensor exhibited a linear refractive index sensitivity of 2150 nm/RIU and 7.136 (a.u.)/RIU in the refractive index of 1.3329-1.3605 interrogated by resonance wavelength and amplitude methods respectively and a single wavelength monitoring method was proposed to investigate the sensing performance of this sensor. Polyadenine diblock and thiolated thrombin aptamers were immobilized on gold nanoparticles and gold films respectively to implement a sandwich optical fiber assay for thrombin. The developed optical fiber SPR sensors were successfully used in the determination of thrombin down to 0.56 nM over a wide range from 2 to 100 nM and showed good selectivity for thrombin, which indicated their potential clinical applications for biomedical samples.

Indexed as

Biosensing TechniquesMetal NanoparticlesGoldOptical FibersSurface Plasmon ResonanceThrombinGoldThrombinBiosensingElectroless platingOptical fiberSurface plasmon resonance

Identifiers

PMID38236393
OpenAlexW4390979012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.