Evidence map›Paper›PMID 38236022›Full record

ReviewHuman vaccines & immunotherapeutics2024

A review of safety and immunogenicity of a novel measles, mumps, rubella (MMR) vaccine.

Nitin Shah, Apurba Ghosh, Kishore Kumar, Trayambak Dutta, Manish Mahajan

Erratum issuedOpen access · goldAbstract readReview
In one paragraph

Review in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Nitin ShahDepartment of Peadiatrics, P.D Hinduja Hospital & Medical Research Centre, Mumbai, India.
Apurba GhoshDepartment of Peadiatrics, Institute of Child Health, Kolkata, India.
Kishore KumarDepartment of Peadiatrics, CloudNine Group of Hospitals, Bengaluru, India.
Trayambak DuttaMedical Affairs, Zydus Lifesciences Ltd., Zydus Corporate Park, Ahmedabad, India.
Manish MahajanMedical Affairs, Zydus Lifesciences Ltd., Zydus Corporate Park, Ahmedabad, India.
Cadila Healthcare (India) · INCloudnine · INInstitute of Child Health · INP. D. Hinduja Hospital and Medical Research Centre · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measles, mumps, and rubella (MMR) are highly infectious viral diseases affecting young children and have high secondary attack rates. Present MMR vaccines show consistent seroconversion rates for anti-measles and anti-rubella antibodies with variable responses for anti-mumps antibodies. Most common strains for MMR vaccines, currently available in India, are the Edmonston-Zagreb measles strain, Leningrad Zagreb (L-Z) mumps strain, and the RA 27/3 rubella strain. L-Z strain of mumps virus has been found to be associated with aseptic meningitis by different studies from different parts of the world including India. Recently, a novel freeze-dried MMR vaccine developed by Zydus Lifesciences (Zyvac MMR) contains Edmonston Zagreb measles strain, Hoshino mumps strain, and RA 27/3 rubella strain. The Hoshino strain is WHO approved and was found to induce interferon gamma production. This review article aims to provide a comprehensive appraisal of the data available on the safety and immunogenicity of the novel MMR vaccine.

Indexed as

MeaslesMumpsRubellaAntibodies, ViralChildChild, PreschoolHumansInfantMeasles-Mumps-Rubella VaccineMeasles VaccineMumps virusRubella VaccineAntibodies, ViralMeasles-Mumps-Rubella VaccineMeasles VaccineRubella Vaccineaseptic meningitisHoshinoIAPIndiaLeningrad ZagrebMMR

Identifiers

PMID38236022
PMCPMC10798359
OpenAlexW4390973713

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.