Evidence map›Paper›PMID 38236006›Full record

ArticleJournal of virology2024

An RNA replicon system to investigate promising inhibitors of feline coronavirus.

Kimberly Schmied, Rosina Ehmann, Claudia Kristen-Burmann, Nadine Ebert, Güliz Tuba Barut, Lea Almeida, Jenna N Kelly, Lisa Thomann, Hanspeter Stalder, Reto Lang and 2 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Kimberly SchmiedInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0000-0002-6158-7074
Rosina EhmannInstitute of Virology, Justus Liebig University Giessen, Giessen, Germany.ORCID 0000-0002-4334-9427
Claudia Kristen-BurmannInstitute of Virology, Justus Liebig University Giessen, Giessen, Germany.
Nadine EbertInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0000-0001-7603-1864
Güliz Tuba BarutInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0000-0002-3863-0775
Lea AlmeidaInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0009-0007-9945-0894
Jenna N KellyInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0000-0001-7265-2233
Lisa ThomannInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0000-0003-3530-0524
Hanspeter StalderInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0000-0003-0763-6469
Reto LangInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0009-0005-9028-0863
Gergely TekesInstitute of Virology, Justus Liebig University Giessen, Giessen, Germany.ORCID 0000-0002-9941-2368
Volker ThielInstitute of Virology and Immunology (IVI), Bern and Mittelhäusern, Switzerland.ORCID 0000-0002-5783-0887
University of Bern · CHJustus-Liebig-Universität Gießen · DE

Funding

Deutsche Forschungsgemeinschaft (DFG) SFB1021Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung (SNF) 310030B_201278
6 · The paper itself

Abstract

Feline infectious peritonitis (FIP) is a fatal feline disease, caused by a feline coronavirus (FCoV), namely feline infectious peritonitis virus (FIPV). We produced a baby hamster kidney 21 (BHK) cell line expressing a serotype I FCoV replicon RNA with a green fluorescent protein (GFP) reporter gene (BHK-F-Rep) and used it as an

Indexed as

Antiviral AgentsCoronavirus, FelineFeline Infectious PeritonitisLactamsLeucineSulfonic AcidsAnimalsCatsRNAAntiviral AgentsGC376LactamsLeucineRNASulfonic Acidsantiviral agentsfeline coronavirusfeline infectious peritonitisreplicon

Identifiers

PMID38236006
PMCPMC10878086
OpenAlexW4390985263

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.