Evidence map›Paper›PMID 38235841›Full record

Observational studyEuropean journal of neurology2024

Embracing the future-is artificial intelligence already better? A comparative study of artificial intelligence performance in diagnostic accuracy and decision-making.

Ângelo Fonseca, Axel Ferreira, Luís Ribeiro, Sandra Moreira, Cristina Duque

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in European journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07493681 (Role of ChatGPT in the Differential Diagnosis of Polyneuropathies and Comparison of Its Performance With That of Peripheral Neuropathy Specialists and Non-specialists), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07493681 completednot on this map

Role of ChatGPT in the Differential Diagnosis of Polyneuropathies and Comparison of Its Performance With That of Peripheral Neuropathy Specialists and Non-specialists

Typeobservational_patient_registrySponsorIstituto Clinico HumanitasRan2023 to 2025Enrolled100ConditionsPolyneuropathiesArmsChatGPT-4o, chatGPT
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Applications of Chatbots in Improving Patient Care Outcomes:Sultan Qaboos University medical journal · 2026
    Article
  3. Article
  4. Large Language Models in Neurological Practice: Real-World Study.Journal of medical Internet research · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ângelo FonsecaNeurology Department, Hospital Pedro Hispano, ULS-Matosinhos, Matosinhos, Portugal.ORCID 0000-0003-0206-0616
Axel FerreiraNeurology Department, Hospital Pedro Hispano, ULS-Matosinhos, Matosinhos, Portugal.ORCID 0000-0003-3792-8542
Luís RibeiroNeurology Department, Hospital Pedro Hispano, ULS-Matosinhos, Matosinhos, Portugal.ORCID 0000-0001-7926-0478
Sandra MoreiraNeurology Department, Hospital Pedro Hispano, ULS-Matosinhos, Matosinhos, Portugal.ORCID 0000-0002-2248-5358
Cristina DuqueNeurology Department, Hospital Pedro Hispano, ULS-Matosinhos, Matosinhos, Portugal.ORCID 0000-0002-4732-0090

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe integration of artificial intelligence (AI) in healthcare has the potential to revolutionize patient care and clinical decision-making. This study aimed to explore the reliability of large language models in neurology by comparing the performance of an AI chatbot with neurologists in diagnostic accuracy and decision-making.

methodsA cross-sectional observational study was conducted. A pool of clinical cases from the American Academy of Neurology's Question of the Day application was used as the basis for the study. The AI chatbot used was ChatGPT, based on GPT-3.5. The results were then compared to neurology peers who also answered the questions-a mean of 1500 neurologists/neurology residents.

resultsThe study included 188 questions across 22 different categories. The AI chatbot demonstrated a mean success rate of 71.3% in providing correct answers, with varying levels of proficiency across different neurology categories. Compared to neurology peers, the AI chatbot performed at a similar level, with a mean success rate of 69.2% amongst peers. Additionally, the AI chatbot achieved a correct diagnosis in 85.0% of cases and it provided an adequate justification for its correct responses in 96.1%.

conclusionsThe study highlights the potential of AI, particularly large language models, in assisting with clinical reasoning and decision-making in neurology and emphasizes the importance of AI as a complementary tool to human expertise. Future advancements and refinements are needed to enhance the AI chatbot's performance and broaden its application across various medical specialties.

Indexed as

Artificial IntelligenceNeurologyCross-Sectional StudiesHumansReproducibility of ResultsSoftwareartificial intelligenceautomated diagnosisautomated treatmentChatGPTclinical reasoning

Identifiers

PMID38235841
PMCPMC11235701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.