Evidence map›Paper›PMID 38235736›Full record

ArticleGut microbes

Tunable control of

Abigail L Reens, Casey M Cosetta, Russell Saur, Olivia Trofimuk, Sarah L Brooker, Martin L Lee, Adam K Sun, Gregory J McKenzie, Julie E Button

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Oligosaccharides from the seeds ofFrontiers in immunology · 2025
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Abigail L ReensProlacta Bioscience, Duarte, CA, USA.
Casey M CosettaProlacta Bioscience, Duarte, CA, USA.
Russell SaurProlacta Bioscience, Duarte, CA, USA.
Olivia TrofimukProlacta Bioscience, Duarte, CA, USA.
Sarah L BrookerProlacta Bioscience, Duarte, CA, USA.
Martin L LeeProlacta Bioscience, Duarte, CA, USA.
Adam K SunProlacta Bioscience, Duarte, CA, USA.
Gregory J McKenzieProlacta Bioscience, Duarte, CA, USA.
Julie E ButtonProlacta Bioscience, Duarte, CA, USA.
University of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Precision engineering of the gut microbiome holds promise as an effective therapeutic approach for diseases associated with a disruption in this microbial community. Engrafting a live biotherapeutic product (LBP) in a predictable, controllable manner is key to the consistent success of this approach and has remained a challenge for most LBPs under development. We recently demonstrated high-level engraftment of

Indexed as

BifidobacteriumGastrointestinal MicrobiomeAnimalsBifidobacterium longum subspecies infantisHumansMiceMilk, HumanOligosaccharidesOligosaccharidesBifidobacteriumB. infantisGut microbiomegut microbiotaHuman milk oligosaccharides (HMO)Live biotherapeutic product (LBP)microbiome modulationsynbiotic

Identifiers

PMID38235736
PMCPMC10798361
OpenAlexW4390975774

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.