ArticleHeadache2024
The impacts of migraine on functioning: Results from two qualitative studies of people living with migraine.
Article in Headache, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Investigating the impact of migraine on short-term and working memory: a systematic review and meta-analysis.Journal of neurology · 2026Pooled it
- Research trends and hotspots in clinical trials of migraine in the past 20 years: bibliometric analysis.Frontiers in neurology · 2024Pooled it
- The Migraine Care Gap: A Qualitative Analysis of Patients' Perspectives on Medical Progress and Persistent Unmet Needs.Pain and therapy · 2026Article
- Article
- Digital Assessment of Objective and Patient-Reported Cognition Across Migraine Phases: Results from the MIND Cohort.medRxiv : the preprint server for health sciences · 2026Article
- Adapting to life with chronic migraine: a qualitative study of lived experiences among multi-ethnic Asian patients.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- Persistent postural-perceptual dizziness versus vestibular migraine: A narrative review.Headache · 2026Review
- The Social Life of Migraine: A Meta-Ethnography of Lived Experience in Adults With Migraine.Health services insights · 2026Review
- Real-world effectiveness of eptinezumab in chronic migraine-increase in good days in three subgroups: psychiatric comorbidities, prior subcutaneous anti-calcitonin gene-related peptide therapy, and migraine-associated brain fog.The journal of headache and pain · 2025Article
- Associations between good days per month and migraine-related disease impact in the real-world: a post hoc analysis from the REVIEW study of eptinezumab in chronic migraine.The journal of headache and pain · 2025Observational
- Exploring the professional and personal impact of migraine: a cross-sectional study in Greece.Journal of oral & facial pain and headache · 2025Article
- Prioritising patient involvement in patient reported outcome measures- a PROMising way to improve headache care.The journal of headache and pain · 2025Review
- Interictal burden in migraine patients at the outset of CGRP monoclonal antibody prevention.The journal of headache and pain · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveTo describe the impact of migraine on functioning based on comprehensive data collection, analysis, and reporting of patients' experiences.
backgroundQualitative research conducted to understand patients' perspectives on living with migraine has often focused on narrow topics or specific groups of patients or has been selectively reported.
methodsQualitative interviews with 71 participants were conducted during two concept elicitation studies as part of the Migraine Clinical Outcome Assessment System (MiCOAS) project, an FDA grant-funded program designed to develop a core set of patient-centered outcome measures for migraine clinical trials. Participants self-reported being diagnosed with migraine by a healthcare professional and participated in semi-structured qualitative interviews about their experiences with the symptoms and impacts of migraine. Interview transcripts were coded to identify and define concepts, which were then grouped into broad domains based on conceptual similarities.
resultsA total of 66 concepts were identified: 12 for physical functioning, 16 for cognitive functioning, 10 for social role functioning, 19 for emotional and psychological functioning, and 9 related to migraine management. Participants described a complex and varied relationship between migraine attack symptoms and impacts on functioning. Impacts from migraine were further influenced by numerous contextual factors, such as people's individual social environments and the level of day-to-day demand for functioning they face.
conclusionFindings showed that migraine impacted individual functioning in multiple ways and the nature of these impacts was dependent on social-contextual factors. The results are being used in the development of core measures designed to improve our understanding of the burden of migraine and the efficacy of migraine therapies. The results also offer new insights and raise new questions about migraine experience that can be used to guide future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.