Evidence map›Paper›PMID 38235555›Full record

ReviewArteriosclerosis, thrombosis, and vascular biology2024

Clot or Not? Reviewing the Reciprocal Regulation Between Lipids and Blood Clotting.

Ziyu Zhang, Maya Rodriguez, Ze Zheng

Open access · bronzeAbstract readReview
In one paragraph

Review in Arteriosclerosis, thrombosis, and vascular biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Atherogenic apolipoprotein C-III may not be as bad as we thought.Journal of thrombosis and haemostasis : JTH · 2026
    Article
  4. Article
  5. Analysis ofInternational journal of molecular sciences · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ziyu ZhangThrombosis & Hemostasis Program, Versiti Blood Research Institute, Milwaukee (M.R., Z. Zhang, Z. Zheng).ORCID 0000-0002-7142-0518
Maya RodriguezThrombosis & Hemostasis Program, Versiti Blood Research Institute, Milwaukee (M.R., Z. Zhang, Z. Zheng).ORCID 0000-0001-7106-1968
Ze ZhengThrombosis & Hemostasis Program, Versiti Blood Research Institute, Milwaukee (M.R., Z. Zhang, Z. Zheng).ORCID 0000-0002-4453-224X
Versiti Blood Center of Wisconsin · USMedical College of Wisconsin · US

Funding

The role of hepatocyte tPA in hepatic VLDL production.R01HL163516 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Ze Zheng · 2022 to 2026
$2.7M
American Heart Association-American Stroke Association 952422 - ZE ZHENGNHLBI NIH HHS R01 HL163516
6 · The paper itself

Abstract

Both hyperlipidemia and thrombosis contribute to the risks of atherosclerotic cardiovascular diseases, which are the leading cause of death and reduced quality of life in survivors worldwide. The accumulation of lipid-rich plaques on arterial walls eventually leads to the rupture or erosion of vulnerable lesions, triggering excessive blood clotting and leading to adverse thrombotic events. Lipoproteins are highly dynamic particles that circulate in blood, carry insoluble lipids, and are associated with proteins, many of which are involved in blood clotting. A growing body of evidence suggests a reciprocal regulatory relationship between blood clotting and lipid metabolism. In this review article, we summarize the observations that lipoproteins and lipids impact the hemostatic system, and the clotting-related proteins influence lipid metabolism. We also highlight the gaps that need to be filled in this area of research.

Indexed as

AtherosclerosisThrombosisBlood CoagulationBlood Coagulation FactorsFibrinolysisHumansLipoproteinsQuality of LifeBlood Coagulation FactorsLipoproteinscardiovascular diseasescoagulationfibrinfibrinolysislipidlipoproteins

Identifiers

PMID38235555
PMCPMC10922732
OpenAlexW4390977091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.