Evidence map›Paper›PMID 38235134›Full record

ArticleFrontiers in immunology2023

The regulatory role of eosinophils in adipose tissue depends on autophagy.

Aref Hosseini, Nina Germic, Nikita Markov, Darko Stojkov, Kevin Oberson, Shida Yousefi, Hans-Uwe Simon

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Aref HosseiniInstitute of Pharmacology, University of Bern, Bern, Switzerland.
Nina GermicInstitute of Pharmacology, University of Bern, Bern, Switzerland.
Nikita MarkovInstitute of Pharmacology, University of Bern, Bern, Switzerland.
Darko StojkovInstitute of Pharmacology, University of Bern, Bern, Switzerland.
Kevin ObersonInstitute of Pharmacology, University of Bern, Bern, Switzerland.
Shida YousefiInstitute of Pharmacology, University of Bern, Bern, Switzerland.
Hans-Uwe SimonInstitute of Pharmacology, University of Bern, Bern, Switzerland.
University of Bern · CHMedizinische Hochschule Brandenburg Theodor Fontane · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Obesity is a metabolic condition that elevates the risk of all-cause mortality. Brown and beige adipose tissues, known for their thermogenic properties, offer potential therapeutic targets for combating obesity. Recent reports highlight the role of immune cells, including eosinophils, in adipose tissue homeostasis, while the underlying mechanisms are poorly understood. Methods: To study the role of autophagy in eosinophils in this process, we used a genetic mouse model lacking autophagy-associated protein 5 ( Results: The absence of Discussion: The data shed light on the importance of autophagy in eosinophils and its impact on adipose tissue homeostasis by suppressing

Indexed as

Adipose TissueEosinophilsAdipocytesAnimalsAutophagyMiceObesityadipose tissuearginase 2Atg5autophagybeigingeosinophilsmacrophages

Identifiers

PMID38235134
PMCPMC10792036
OpenAlexW4390540879

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.