Evidence map›Paper›PMID 38235033›Full record

ArticleThe Neurohospitalist2024

41-Year-Old Male with Sub-Acute Encephalopathy, Seizures, and End Stage Renal Disease: A Unifying Diagnosis and Response to Therapy.

Tameena Wais, Karen P Ibarra, Dattanand M Sudarshana, Meghana Eswarappa, Meyeon Park, Renata C Gallagher, Brian Tsui, Stephanie Teixeira, S Andrew Josephson, Megan Richie

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Neurohospitalist, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Tameena WaisDepartment of Neurology, University of Arizona, Tucson, AZ, USA.ORCID https://orcid.org/0009-0000-0786-0642
Karen P IbarraDepartment of Neurology and the Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
Dattanand M SudarshanaDepartment of Neurology and the Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
Meghana EswarappaDivision of Nephrology, Department of Medicine, University of California, San Francisco, CA, USA.
Meyeon ParkDivision of Nephrology, Department of Medicine, University of California, San Francisco, CA, USA.
Renata C GallagherDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Brian TsuiDepartment of Radiology, University of California, San Francisco, CA, USA.
Stephanie TeixeiraDepartment of Radiology, University of California, San Francisco, CA, USA.
S Andrew JosephsonDepartment of Neurology and the Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
Megan RichieDepartment of Neurology and the Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.
University of California, San Francisco · USUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a case of a 41-year-old male with a history of end-stage renal disease, hypertension, epilepsy, ischemic stroke, and traumatic brain injury transferred to our tertiary care center for subacute, progressive cognitive impairment. He was found to have disproportionate brain atrophy, focal seizures, and refractory hypertension. Given suspicion for an underlying genetic etiology, a genetic panel for progressive renal disease was sent, revealing two known pathogenic variants in a gene for a cobalamin metabolism disorder, Cobalamin C deficiency. He was started on targeted metabolic supplementation with subsequent improvement in his cognition. Our case highlights the crucial need to expand diagnostic workup to include genetic and metabolic causes in patients with neurologic disease, atypical features, relevant family history and multi-organ dysfunction.

Indexed as

brain diseasesclinical specialtyepilepsyheredodegenerative disordersmetabolicnervous systemneurodegenerative diseasesneurohospitalistseizures

Identifiers

PMID38235033
PMCPMC10790610
OpenAlexW4385567773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.