Evidence map›Paper›PMID 38234816›Full record

ArticlebioRxiv : the preprint server for biology2023

Ultrastructural, metabolic and genetic determinants of the acquisition of macrolide resistance by

Xueqing Wu, Babek Alibayov, Xi Xiang, Santiago M Lattar, Fuminori Sakai, Austin A Medders, Brenda Antezana, Lance Keller, Ana G J Vidal, Yih-Ling Tzeng and 4 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Endocrine control of gill ionocyte function in euryhaline fishes.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Xueqing WuDepartment of Infectious Diseases, Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310052, China.
Babek AlibayovDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson MS 39056, United States.
Xi XiangDepartment of Clinical Laboratory, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua 321000, China.
Santiago M LattarHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta GA 30322, United States.
Fuminori SakaiHubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta GA 30322, United States.
Austin A MeddersDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson MS 39056, United States.
Brenda AntezanaDepartment of Medicine, School of Medicine, Emory University, Atlanta GA 30322, United States.
Lance KellerDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson MS 39056, United States.
Ana G J VidalDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson MS 39056, United States.
Yih-Ling TzengDepartment of Medicine, School of Medicine, Emory University, Atlanta GA 30322, United States.
D Ashley RobinsonDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson MS 39056, United States.
David StephensDepartment of Medicine, School of Medicine, Emory University, Atlanta GA 30322, United States.
Yunsong YuDepartment of Infectious Diseases, Regional Medical Center for National Institute of Respiratory Diseases, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310052, China.
Jorge E VidalDepartment of Microbiology and Immunology, University of Mississippi Medical Center, Jackson MS 39056, United States.
University of Mississippi Medical Center · USEmory University · USSir Run Run Shaw Hospital · CNZhejiang University · CN

Funding

Training and Mentoring Core P20GM103476 · NIGMS · UNIVERSITY OF SOUTHERN MISSISSIPPI · PI MICHAEL R GARRETT · 2012 to 2026
$60.2M
Pilot Projects ProgramP30GM149404 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI John E Hall · 2023 to 2026
$6.3M
Population Dynamics of S. pneumoniae vaccine serotypes on human pharyngeal cellsR21AI112768 · NIAID · EMORY UNIVERSITY · PI VIDAL, JORGE EUGENIO · 2015 to 2016
$429k
NIAID NIH HHS R21 AI112768NIGMS NIH HHS P20 GM103476NIGMS NIH HHS P30 GM149404
6 · The paper itself

Abstract

Aim: Methods and Results: Whole genome analysis was conducted for 128 macrolide-resistant pneumococcal isolates to identify the presence of MEGA (44.5%, 57/128) or Conclusions: Extracellular and intracellular pneumococcal clusters facilitate the acquisition of full-length ICE at a rF higher than that of typical transformation events, involving distinct metabolic changes that present potential targets for interventions.

Identifiers

PMID38234816
PMCPMC10793443
OpenAlexW4390403010

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.