Evidence map›Paper›PMID 38234814›Full record

ArticlebioRxiv : the preprint server for biology2023

Identification of a myofibroblast differentiation program during neonatal lung development.

Yongjun Yin, Jeffrey R Koenitzer, Debabrata Patra, Sabine Dietmann, Peter Bayguinov, Andrew S Hagan, David M Ornitz

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yongjun YinDepartments of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0003-1240-2640
Jeffrey R KoenitzerMedicine, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-4556-8455
Debabrata PatraDepartments of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0001-8606-1573
Sabine DietmannDepartments of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-1968-9309
Peter BayguinovNeuroscience, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0002-5365-7490
Andrew S HaganDepartments of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0003-2265-3355
David M OrnitzDepartments of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0003-1592-7629
Washington University in St. Louis · US

Funding

Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0M
FGF18 regulation of postnatal lung developmentR01HL154747 · NHLBI · WASHINGTON UNIVERSITY · PI ORNITZ, DAVID M · 2020 to 2023
$2.5M
Microfibril-associated glycoproteins attenuating pulmonary fibrosisK08HL159418 · NHLBI · WASHINGTON UNIVERSITY · PI Jeffrey Koenitzer · 2022 to 2026
$857k
NCI NIH HHS P30 CA091842NHLBI NIH HHS K08 HL159418NHLBI NIH HHS R01 HL154747
6 · The paper itself

Abstract

Alveologenesis is the final stage of lung development in which the internal surface area of the lung is increased to facilitate efficient gas exchange in the mature organism. The first phase of alveologenesis involves the formation of septal ridges (secondary septae) and the second phase involves thinning of the alveolar septa. Within secondary septa, mesenchymal cells include a transient population of alveolar myofibroblasts (MyoFB) and a stable but poorly described population of lipid rich cells that have been referred to as lipofibroblasts or matrix fibroblasts (MatFB). Using a unique

Indexed as

Adventitial fibroblastAlveologenesisLipofibroblastMatrix fibroblastMyofibroblastSecondary septaSingle cell genomic analysis

Identifiers

PMID38234814
PMCPMC10793446
OpenAlexW4390309688

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.