ArticleInternational journal of cardiology. Heart & vasculature2024
Association between sodium-to-potassium ratio in spot urine and hospitalization due to heart failure in high-risk Japanese patients.
Article in International journal of cardiology. Heart & vasculature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: In Japanese cardiovascular (CV) high-risk patients, the ESPRIT Methods: This is a post-hoc analysis of a previously reported ESPRIT study (n = 520, 60 HF hospitalizations). Results: Receiver operating curve analysis yielded optimal Na/K ratio cut-off value of 2.9 for detecting HF hospitalization. Kaplan-Meier curve showed that high Na/K ratio in spot urine was associated with increased HF hospitalization (p < 0.001). Cox proportional hazards model analysis revealed that high Na/K ratio was associated with HF hospitalization with a hazard ratio of 2.97 (confidence interval: 1.67-5.61). An association between high Na/K ratio and HF hospitalization remained after adjustments for Na/Cr ratio in spot urine or the use of diuretics. Conclusion: The Na/K ratio in spot urine is associated with HF hospitalization in high-risk Japanese patients.
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