Evidence map›Paper›PMID 38234604›Full record

ArticleActa naturae

RIPK3 Expression in Fibroblasts in an in vivo and in vitro Skin Wound Model: A Controversial Result.

I S Izumov, M S Shitova, M S Sabirov, S A Sheleg, O L Cherkashina, E P Kalabusheva, E A Vorotelyak, E I Morgun

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

I S IzumovKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
M S ShitovaKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
M S SabirovKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
S A ShelegKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
O L CherkashinaKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
E P KalabushevaKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
E A VorotelyakKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
E I MorgunKoltzov Institute of Developmental Biology of Russian Academy of Sciences, Moscow, 119334 Russian Federation.
Koltzov Institute of Developmental Biology · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the major problems of regenerative medicine is the development of hypertrophic scars and keloids. The protein kinase RIPK3 is involved in necroptosis; however, recent evidence indicates that it also has non-canonical functions, including its involvement in the development of renal fibrosis. The aim of our work was to study the expression of RIPK3 in mouse and human skin models of fibrotic processes. A subpopulation of RIPK3+Vim+ cells was found in both human keloid and a mouse wound, with the cell number being significantly greater in the mouse wound bed compared to healthy skin. Real-time polymerase chain reaction (RT-PCR) detected expression of the

Indexed as

cell culturefibroblastskeloidRIPK3scarringskin

Identifiers

PMID38234604
PMCPMC10790357
OpenAlexW4390988992

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.