Evidence map›Paper›PMID 38234461›Full record

ArticleMaterials today. Bio2024

Itaconate and citrate releasing polymer attenuates foreign body response in biofabricated cardiac patches.

Dawn Bannerman, Simon Pascual-Gil, Scott Campbell, Richard Jiang, Qinghua Wu, Sargol Okhovatian, Karl T Wagner, Miles Montgomery, Michael A Laflamme, Locke Davenport Huyer and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Itaconate and its derivatives in human health and diseases.Signal transduction and targeted therapy · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Dawn BannermanChemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
Simon Pascual-GilInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Scott CampbellChemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
Richard JiangInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Qinghua WuInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Sargol OkhovatianInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.
Karl T WagnerChemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
Miles MontgomeryChemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
Michael A LaflammeMcEwen Stem Cell Institute, University Health Network, Toronto, ON, Canada.
Locke Davenport HuyerApplied Oral Sciences, Dalhousie University, Halifax, NS, Canada.
Milica RadisicChemical Engineering and Applied Chemistry, University of Toronto, Toronto, ON, Canada.
University Health Network · CADalhousie University · CA

Funding

Engineering Vascularized Cardiac MuscleR01HL076485 · NHLBI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Gordana Vunjak-Novakovic · 2005 to 2026
$9.2M
NHLBI NIH HHS R01 HL076485
6 · The paper itself

Abstract

Application of cardiac patches to the heart surface can be undertaken to provide support and facilitate regeneration of the damaged cardiac tissue following ischemic injury. Biomaterial composition is an important consideration in the design of cardiac patch materials as it governs host response to ultimately prevent the undesirable fibrotic response. Here, we investigate a novel patch material, poly (itaconate-

Indexed as

BiomaterialCardiac patchIschemia reperfusion injuryMyocardial infarctionPolymer

Identifiers

PMID38234461
PMCPMC10792972
OpenAlexW4389903484

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.