Evidence map›Paper›PMID 38234330›Full record

ArticleBiotechnology reports (Amsterdam, Netherlands)2024

Immunogenicity of a recombinant plant-produced respiratory syncytial virus F subunit vaccine in mice.

Nuttapat Pisuttinusart, Balamurugan Shanmugaraj, Chanya Srisaowakarn, Chutitorn Ketloy, Eakachai Prompetchara, Arunee Thitithanyanont, Waranyoo Phoolcharoen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biotechnology reports (Amsterdam, Netherlands), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nuttapat PisuttinusartCenter of Excellence in Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, Thailand.
Balamurugan ShanmugarajDepartment of Biotechnology, Bharathiar University, Coimbatore - 641046, Tamil Nadu, India.
Chanya SrisaowakarnDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Chutitorn KetloyCenter of Excellence in Vaccine Research and Development (Chula VRC), Chulalongkorn University, Bangkok 10330, Thailand.
Eakachai PrompetcharaCenter of Excellence in Vaccine Research and Development (Chula VRC), Chulalongkorn University, Bangkok 10330, Thailand.
Arunee ThitithanyanontDepartment of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand.
Waranyoo PhoolcharoenCenter of Excellence in Plant-produced Pharmaceuticals, Chulalongkorn University, Bangkok 10330, Thailand.
Chulalongkorn University · THMahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) is a highly infectious respiratory virus that causes serious illness, particularly in young children, elderly people, and those with immunocompromised individuals. RSV infection is the leading cause of infant hospitalization and can lead to serious complications such as pneumonia and bronchiolitis. Currently, there is an RSV vaccine approved exclusively for the elderly population, but no approved vaccine specifically designed for infants or any other age groups. Therefore, it is crucial to continue the development of an RSV vaccine specifically tailored for these populations. In this study, the immunogenicity of the two plant-produced RSV-F Fc fusion proteins (Native construct and structural stabilized construct) were examined to assess them as potential vaccine candidates for RSV. The RSV-F Fc fusion proteins were transiently expressed in

Indexed as

Nicotianabenthamianaplant-produced recombinant proteinRespiratory syncytial virusSubunit vaccine

Identifiers

PMID38234330
PMCPMC10793081
OpenAlexW4390141654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.