Evidence map›Paper›PMID 38234123›Full record

ArticleESC heart failure2024

Pre-emptive treatment of heart failure exacerbations in patients managed with the HeartLogic™ algorithm.

Rodrigue Garcia, Daniel Gras, Jacques Mansourati, Pascal Defaye, Arnaud Bisson, Serge Boveda, Estelle Gandjbakhch, Matthieu Gras, Jean-Pierre Gueffet, Caroline Himbert and 11 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in ESC heart failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07544771 (HeartLogic™ Evaluation for Remote Monitoring vs. Office-based Follow-up in Patients With Heart Failure.), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07544771 narecruitingnot on this mapstarted 2026, after this paper: background citation

HeartLogic™ Evaluation for Remote Monitoring vs. Office-based Follow-up in Patients With Heart Failure.

TypeinterventionalSponsorPoitiers University HospitalRan2026 to 2029Enrolled578ConditionsHeart FailureArmsAlert-guided remote follow-up, Traditional follow up
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 4 countries.

Rodrigue GarciaDepartment of Cardiology, University Hospital of Poitiers, Poitiers, France.ORCID https://orcid.org/0000-0001-9350-2437
Daniel GrasDepartment of Cardiology, Hôpital privé du Confluent, Nantes, France.
Jacques MansouratiDepartment of Cardiology, University Hospital of Brest, Brest, France.
Pascal DefayeDepartment of Cardiology, University Hospital Grenoble Alpes, Grenoble, France.
Arnaud BissonDepartment of Cardiology, University Hospital of Tours, Chambray-lès-Tours, France.
Serge BovedaDepartment of Cardiology, Clinique Pasteur, Toulouse, France.
Estelle GandjbakhchDepartment of Cardiology, Hôpital la Pitié Salpétrière, Paris, France.
Matthieu GrasDepartment of Cardiology, University Hospital of Poitiers, Poitiers, France.
Jean-Pierre GueffetDepartment of Cardiology, Hôpital privé du Confluent, Nantes, France.
Caroline HimbertDepartment of Cardiology, Hôpital la Pitié Salpétrière, Paris, France.
Peggy JaconDepartment of Cardiology, University Hospital Grenoble Alpes, Grenoble, France.
Pierre KhattarDepartment of Cardiology, Hospital of Lorient, Lorient, France.
Benoit LequeuxDepartment of Cardiology, University Hospital of Poitiers, Poitiers, France.
Anthony LiDepartment of Cardiology, St. George's University of London, Cranmer Terrace, London, UK.
Vincent MansouratiDepartment of Cardiology, University Hospital of Brest, Brest, France.
Damien MinoisDepartment of Cardiology, University Hospital of Nantes, Nantes Cedex 1, France.
Eloi MarijonDepartment of Cardiology, Hôpital Européen Georges Pomipdou, Paris, France.
Bertrand PierreDepartment of Cardiology, University Hospital of Tours, Chambray-lès-Tours, France.
Vincent ProbstDepartment of Cardiology, University Hospital of Nantes, Nantes Cedex 1, France.
Bruno DegandDepartment of Cardiology, University Hospital of Poitiers, Poitiers, France.
HeartLogic™ France Cohort Study Investigators
Université de Poitiers · FRCentre Hospitalier Régional Universitaire de Brest · FRCentre Hospitalier Universitaire de Grenoble · FRCentre Hospitalier Universitaire de Nantes · FRHôpital privé du Confluent · FRSorbonne Université · FRUniversité de Tours · FRCentre Hospitalier de Bretagne Sud · FRHôpital Européen · FRSt George's, University of London · GBVrije Universiteit Brussel · BE

Funding

Boston Scientific through an Investigator-Sponsored Research Program
6 · The paper itself

Abstract

aimsHeart failure (HF) is a chronic disease affecting 64 million people worldwide and places a severe burden on society because of its mortality, numerous re-hospitalizations and associated costs. HeartLogic™ is an algorithm programmed into implanted devices incorporating several biometric parameters which aims to predict HF episodes. It provides an index which can be monitored remotely, allowing pre-emptive treatment of congestion to prevent acute decompensation. We aim to assess the impact and security of pre-emptive HF management, guided by the HeartLogic™ index. METHODS AND

resultsThe HeartLogic™ France Cohort Study is an investigator-initiated, prospective, multi-centre, non-randomized study. Three hundred ten patients with a history of HF (left ventricular ejection fraction ≤40%; or at least one episode of clinical HF with elevated NT-proBNP ≥450 ng/L) and implanted with a cardioverter defibrillator enabling HeartLogic™ index calculation will be included across 10 French centres. The HeartLogic™ index will be monitored remotely for 12 months and in the event of a HeartLogic™ index ≥16, the local investigator will contact the patient for assessment and adjust HF treatment as necessary. The primary endpoint is unscheduled hospitalization for HF. Secondary endpoints are all-cause mortality, cardiovascular death, HF-related death, unscheduled hospitalizations for ventricular or atrial arrhythmia and HeartLogic™ index evolution over time. Blood samples will be collected for biobanking, and quality of life will be assessed. Finally, the safety of a HeartLogic™-triggered strategy for initiating or increasing diuretic therapy will be assessed. A blind and independent committee will adjudicate the events.

conclusionsThe HeartLogic™ France Cohort Study will provide robust real-world data in a cohort of HF patients managed with the HeartLogic™ algorithm allowing pre-emptive treatment of heart failure exacerbations.

Indexed as

Heart FailureQuality of LifeAlgorithmsBiological Specimen BanksCohort StudiesHumansProspective StudiesStroke VolumeVentricular Function, LeftConnected devicesHeart failureHospitalizationMortalityPredictionPre‐emptive actionRemote monitoring

Identifiers

PMID38234123
PMCPMC10966255
OpenAlexW4390983908

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.